Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics

• Type: Another Publication in an International Scientific Journal
• Date: 2021

Authors

Petit, RG (Author) Other; Cano, A (Author) Other; Ortiz, A (Author) Other; Espina, M (Author) Other; Prat, J (Author) Other; Munoz, M (Author) Other; Severino, P (Author) Other; Souto, EB (Author) Other; Garcia, ML (Author) Other; Pujol, M (Author) Other; Sanchez Lopez, E (Author) Other

Journal

Title: International Journal Of Molecular Sciences

Vol. 22 No. 9

Final page: 4983

ISSN: 1661-6596

Publisher: MDPI

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Scientific classification

CORDIS: Health sciences

Other information

Authenticus ID: P-00T-XD0

DOI: 10.3390/ijms22094983

Abstract (EN): Research in the pathogenesis of inflammatory skin diseases, such as skin dermatitis and psoriasis, has experienced some relevant breakthroughs in recent years. The understanding of age-related factors, gender, and genetic predisposition of these multifactorial diseases has been instrumental for the development of new pharmacological and technological treatment approaches. In this review, we discuss the molecular mechanisms behind the pathological features of psoriasis, also addressing the currently available treatments and novel therapies that are under clinical trials. Innovative therapies developed over the last 10 years have been researched. In this area, advantages of nanotechnological approaches to provide an effective drug concentration in the disease site are highlighted, together with microneedles as innovative candidates for drug delivery systems in psoriasis and other inflammatory chronic skin diseases.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 25