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link to PHD Thesis (microbiology-18377)






























































































International Journals
2015 2014 2013 2012 2011 2010


2015
  • N-modified TiO2 photocatalytic activity towards diphenhydramine degradation and Escherichia coli inactivation in aqueous solutions
    Monteiro RAR, Miranda SM, Vilar VJP, Pastrana-Martínez LM, Tavares PB, Boaventura RAR, Faria JL, Pinto E, Silva AMT
    Applied Catalysis B-Environmental. 162: 66-74. 2015




2014
  • Activity of Thymus caespititius essential oil and α-terpineol against yeasts and filamentous fungi
    Pinto E, Gonçalves MJ, Oliveira P, Coelho J, Cavaleiro C, Salgueiro L
    Industrial Crops and Products, 62: 107-112. 2014

  • Synthesis and antimicrobial activity of novel 5-amino imidazole-4-carboxamidrazones
    Ribeiro AI, Gabriel C, Cerqueira F, Maia M, Pinto E, Sousa JC, Medeiros R, M. Proença MF, Dias AM
    Bioorganic & Medicinal Chemistry Letters. 2014
    DOI:10.1016/j.bmcl.2014.08.025.

  • Development of a FTIR-ATR based model for typing clinically relevant Acinetobacter baumannii clones belonging to ST98, ST103, ST208 and ST218.
    Sousa C, Silva L, Grosso F, Lopes J, Peixe L.
    Journal of Photochemistry and Photobiology B Biology;
    DOI:http://dx.doi.org/10.1016/j.jphotobiol.2014.02.015 2014

  • Linezolid-Resistant Staphylococcus epidermidis, Portugal, 2012.
    Barros M, Branquinho R, Grosso F, Peixe L, Novais C.
    Emerg. Infect. Dis. 2014.
    DOI: http://dx.doi.org/10.3201/eid2005.130783

  • MALDI-TOF mass spectrometry as a tool for the discrimination of high-risk Escherichia coli clones from phylogenetic groups B2 (ST131) and D (ST69, ST405, ST393).
    Novais A, Sousa C, Dios Caballero J, Fernandez-Olmos A, Lopes J, Ramos H, Coque TM, Cantón R, Peixe L.
    Eur. J. Clin. Microb. Inf. Diseas.
    DOI:10.1007/s10096-014-2071-5

  • Discrimination of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex species by Fourier transform infrared spectroscopy.
    Sousa C, Silva L, Grosso F, Nemec A, Lopes J, Peixe L.
    Eur. J. Clin. Microb. Inf. Diseas. 2014.
    DOI:10.1007/s10096-014-2078-y

  • Co-transfer of resistance to high concentrations of copper and first-line antibiotics among Enterococcus from different origins (humans, animals, the environment and foods) and clonal lineages.
    Silveira E, Freitas, AR , Antunes P, Barros M, Campos J, Coque TM, Peixe L, Novais C.
    J Antimicrob. Chemother. 2014.
    DOI:10.1093/jac/dkt479

  • Pet veterinarians have no increased risk of hepatitis E compared to the general population.
    Mesquita JR, Valente-Gomes G, Conceição-Neto N, Nascimento MSJ
    J Med Virol. 86 (6):954-6. 2014

  • Feline fecal virome reveals novel and prevalent enteric viruses.
    Ng TFF, Mesquita JR, Nascimento MSJ, Kondov NO, Wong W, Reuter G, Knowles NJ, Vega E, Esona MD, Deng X, Vinjé J, Delwart E.
    Vet Microbiol. 171(1-2):102-11. 2014

  • Seroprevalence of canine norovirus in 14 European countries.
    Mesquita JR, Delgado I, Costantini V, Heenemann K, Vahlenkamp TW, Vinjé J, Nascimento MSJ
    Clin Vaccine Immunol. 21(6):898-900. 2014

  • The enterovirus protease inhibitor rupintrivir exerts broad-spectrum anti-norovirus activity and clears cells from the norovirus replicon
    Rocha-Pereira J, Nascimento MS, Ma Q, Hilgenfeld R, Neyts J, Jochmans D
    Antimicrob Agents Chemother. Jun 2. pii: AAC.02546-13. [Epub ahead of print] 2014

  • First report of chronic hepatitis E in renal transplant recipients in Portugal.
    Breda F, Cochicho J, Mesquita JR, Bento A, Louro E, Nascimento MSJ, Cipriano MA, Leitão J, Gomes HV, Carvalho A
    Journal of Infection in Developing Countries (accepted) 2014

  • Norovirus GII.4 antibodies in the Portuguese population.
    Mesquita JR, Nascimento MSJ
    Journal of Infection in Developing Countries (accepted). 2014

  • Evaluation of Etest performed in Mueller-Hinton agar supplemented with glucose for antifungal susceptibility testing of clinical isolates of filamentous fungi.
    Pinto E, Lago M, Branco L, Vale-Silva LA, Pinheiro MD.
    Mycopathologia, 177(3-4):157-66. 2014

  • Patulin assessment and fungi identification in organic and conventional fruits and derived products.
    Cunha SC, Faria MA, Pereira VL, Oliveira TM, Lima AC, Pinto E.
    Food Control, 44:185-90. 2014

  • Does fungicide application in vineyards induce resistance to medical azoles in Aspergillus species?
    Lago M, Aguiar A, Natário A, Fernandes c, Faria M, Pinto E.
    Environ Monit Assess, DOI 10.1007/s10661-014-3804-8. 2014




2013
  • Diverse high-risk B2 and D Escherichia coli clones depicted by Fourier Transform Infrared Spectroscopy.
    Sousa C, Novais A, Magalhães A, Lopes J, Peixe L.
    Scientific Reports. 3:3278. 2013
    DOI:10.1038/srep03278.

  • Clinically relevant multidrug resistant Salmonella enterica in swine and meat handlers at the abattoir.
    Gomes-Neves E, Antunes P, Manageiro V, Gartner F, Caniça M, Costa JMC, Peixe L.
    Veterinary Microbiology. 2013.
    DOI:http://dx.doi.org/10.1016/j.vetmic.2013.10.017

  • Blue-CARBA: an easy biochemical test to detect diverse carbapenemase producers directly from bacterial cultures.
    Pires J; Novais A; Peixe L.
    J Clin Microbiol. 2013
    DOI:10.1128/JCM.01634-13

  • Long-term dissemination of acquired AmpC ß-lactamases among Klebsiella spp. and Escherichia coli in Portuguese clinical settings.
    Freitas F; Machado E; Ribeiro TG; Novais A; Peixe L.
    Eur. J. Clin. Microb. Inf. Diseas. 2013.

  • Microbiological quality of ready-to-eat salads: An underestimated vehicle of bacteria and clinically relevant antibiotic resistance genes.
    Campos J; Mourão J; Pestana N; Peixe L; Novais C; Antunes P.
    International Journal of Food Microbiology 166(3):464-470. 2013
    doi: 10.1016/j.ijfoodmicro.2013.08.005.

  • Detection of VIM-34, a novel VIM-1 variant identified in the intercontinental ST15 Klebsiella pneumoniae clone.
    Rodrigues C; Novais A; Machado E; Peixe L. V.
    J Antimicrob. Chemother. 2013.
    doi: 10.1093/jac/dkt314.

  • Spread of multidrug resistant Enterococcus to animals and humans: an underestimated role for pig farms environment.
    Novais C; Freitas AR.; Silveira E; Antunes P; Silva R; Coque TM; Peixe L.
    J Antimicrob. Chemother. 2013
    DOI:10.1093/jac/dkt289.

  • IncI1/ST3 and IncN/ST1 plasmids drive the spread of blaTEM-52 and blaCTX-M-1/-32 in diverse Escherichia coli clones from different piggeries.
    Rodrigues C, Machado E, Peixe L, Novais A.
    J Antimicrob Chemother. 13(1):144. 2013
    DOI:10.1186/1471-2180-13-144.

  • Diversity and biofilm-production ability among isolates of Escherichia coli phylogroup D belonging to ST69, ST393 and ST405 clonal groups.
    Novais A, Vuotto C, Pires J, Montenegro C, Donelli G, Coque TM, Peixe L.
    BMC Microbiology. 13(1):144. 2013

  • Commensal Enterobacteriaceae as reservoirs of extended-spectrum beta-lactamases, integrons, and sul genes in Portugal.
    Machado E, Coque TM, Cantón R, Sousa JC, Peixe L.
    Front Microbiol. Apr 8;4:80. 2013
    doi: 10.3389/fmicb.2013.00080.

  • Microevolutionary events involving narrow host plasmids influences local fixation of vancomycin-resistance in Enterococcus populations.
    Freitas AR, Novais C, Tedim AP, Francia MV, Baquero F, Peixe L, Coque TM.
    PLoS One. 8(3):e60589. 2013
    doi: 10.1371/journal.pone.0060589.

  • Antibodies to hepatitis E virus in Portuguese mothers and their newborns.
    Mesquita JR, Conceição-Neto N, Valente-Gomes G, Gonçalves G, Nascimento MSJ.
    J Med Virol. 85 (8):1377-8. 2013

  • Presence of antibodies against genogroup VI norovirus in humans.
    Mesquita JR, Costantini VP, Cannon JL, Lin S-C, Nascimento MSJ, Vinje J
    Virol J. 10:176. 2013

  • Acute hepatitis e complicated by Guillain-Barré syndrome in Portugal.
    Santos L, J R Mesquita, N Rocha Pereira, C Lima-Alves, R Serrão, P Figueiredo, J Reis, J Simões, Nascimento MS, A Sarmento.
    December 2012 – A case report. Eurosurveillance 18 (34). 2013

  • Sulfated small molecules targeting EBV in Burkitt lymphoma: From in silico screening to the evidence of in vitro effect on viral episomal DNA.
    Lima RT, Seca H, Palmeira A, Fernandes MX, Castro F, Correia-da-Silva M, Nascimento MS, Sousa E, Pinto M, Vasconcelos MH.
    Chem Biol Drug Des. 81(5):631-44. 2013

  • Natural compounds with cell growth inhibitory activity in human tumor cell lines.
    Cazal CM, Choosang K, Severino VG, Fernandes JB, da Silva MF, Vieira PC, Nascimento MS, Almeida GM, Vasconcelos MH, Pakkong P, Pinto MM.
    Anticancer Agents Med Chem. 13(10):1582-9. 2013

  • The viral polymerase inhibitor 2’-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model.
    Rocha-Pereira J, Jochmans D, Debing Y, Verbeken E, Nascimento MSJ, Neyts J
    J. Virol. 87(21):11798-11805. 2013

  • Assessment of Indoor Airborne Contamination in a Wastewater Treatment Plant.
    Teixeira JV, Miranda S, Monteiro RAR, Lopes FVS, Madureira J, Silva GV, Pestana N, Pinto E, Vilar VJP, Boaventura RAR.
    Environ Monit Assess, 185(1):59-72. 2013

  • Antifungal activity of Ferulago capillaris essential oil against and dermatophyte species.
    Pinto E, Hrimpeng K, Lopes G, Vaz S, Gonçalves MJ, Cavaleiro C, Salgueiro L.
    Eur J Clin Microbiol, 32(10):1311-20. 2013

  • Chemical study and biological activity evaluation of two azorean macroalgae: Ulva rigida and Gelidium microdon.
    Silva M, Vieira LMM, Almeida AP, Silva MAS, Seca AML, Barreto MC, Neto AI, Pedro M, Pinto E, Kijjoa A.
    Oceanography, open acess 1(1). 2013

  • Antifungal activity of phlorotannins against dermatophytes and yeasts: approaches to the mechanism of action and influence on Candida albicans virulence factor.
    Lopes G, Pinto E, Andrade PB, Valentão P.
    PLOS ONE, 8(8), e72203. 2013

  • Antifungal activity of the essential oil of Thymus villosus subsp. lusitanicus against Candida, Cryptococcus, Aspergillus and dermatophyte species.
    Pinto E, Gonçalves MJ, Hrimpeng K, Pinto J, Vaz S, Vale-Silva LA, Cavaleiro C, Salgueiro L.
    Ind Crops Prod, 51:93-9. 2013

2012
  • The public health risks of enterobacterial isolates producing extended-spectrum ß-lactamases (ESBL) or AmpC ß-lactamases in food and food-producing animals: An EU perspective of epidemiology, analytical methods, risk factors and control options.
    Liebana E., Carattoli A, Coque TM, Hasman H, Magiorakos AP, Mevius D, Peixe L, Poirel L., Schuepbach-Regula G., Torneke K, Torren-Edo J., Torres C., Threlfall J.
    Clinical Infectious Diseases. Dec 14. 2012
    [Epub ahead of print].

  • Identification of carbapenem-resistant Acinetobacter baumannii clones using infrared spectroscopy.
    Sousa C, Grosso F, Meirinhos-Soares L, Peixe L, Lopes J.
    J Biophotonics. 2012.
    doi: 10.1002/jbio.201200075.

  • Salmonella enterica serotype Bovismorbificans, a new host for CTX-M-9.
    Antunes P, Mourão J, Alves T, Campos J, Novais C, Novais A, Peixe L.
    Int J Antimicrob Agents. 41(1):91-3. 2013
    doi: 10.1016/j.ijantimicag.2012.09.009.
  • A tet(S/M) hybrid from CTn6000 and CTn916 recombination.
    Novais C, Freitas AR, Silveira E, Baquero F, Peixe L, Roberts AP, Coque TM.
    Microbiology. Nov;158(Pt 11):2710-1. 2012
    doi: 10.1099/mic.0.062729-0.

  • Different genetic supports for the tet(S) gene in Enterococci.
    Novais C, Freitas AR, Silveira E, Baquero F, Peixe L, Roberts AP, Coque TM.
    Antimicrob Agents Chemother. Nov;56(11):6014-8. 2012
    doi: 10.1128/AAC.00758-12.

  • Characterization of extended-spectrum beta-lactamases, antimicrobial resistance genes, and plasmid content in Escherichia coli isolates from different sources in Rio de Janeiro, Brazil.
    Queiroz LPM, Antunes P, Mourão J, Merquior VLC, Machado E, Peixe LV.
    Diagnostic Microbiology and Infectious Diseases. 74:91-4. 2012
    doi: 10.1016/j.diagmicrobio.2012.05.019.

  • Spread of an OmpK36-modified ST15 Klebsiella pneumoniae variant during an outbreak involving multiple carbapenem-resistant Enterobacteriaceae species and clones.
    Novais A, Rodrigues C, Branquinho R, Antunes P, Grosso F, Boaventura L, Ribeiro G, Peixe L.
    Eur J Clin Microbiol Infect Dis. 2012.

  • Salmonella cross-contamination in swine abattoirs in Portugal: carcasses, meat and meat handlers.
    Gomes-Neves E, Antunes P, Tavares A, Themudo P, Cardoso MF, Gärtner F, Costa JM, Peixe L.
    Int J Food Microbiol. 157(1):82-7. 2012

  • Role of Common blaOXA-24/OXA-40-Carrying Platforms and Plasmids in the Spread of OXA-24/OXA-40 among Acinetobacter species clinical isolates.
    Grosso F, Quinteira S, Poirel L, Novais A, Peixe L.
    Antimicrob Agents Chemother. 56(7):3969-72. 2012

  • Characterization of globally spread Escherichia coli ST131 isolates (1991-2010).
    Novais Â, Pires J, Ferreira H, Costa L, Montenegro C, Vuotto C, Donelli G, Coque TM, Peixe L.
    Antimicrob Agents Chemother. 56(7):3973-6. 2012

  • Solid-phase synthesis of 2’-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor cell lines
    Neves MP, Cravo S, Lima RT, Vasconcelos MH, Nascimento MSJ, Silva AMS, Pinto M, Cidade H, Corrêa AG.
    Bioorg. Med. Chem. 20:25-33. 2012

  • Gastroenteritis outbreak associated with fecal shedding of canine norovirus in a portuguese kennel following introduction of imported dogs from Russia.
    Mesquita JR, Nascimento MSJ.
    Transboundary and Emerging Diseases. 59 (5): 456–459. 2012

  • Prenylated xanthones: antiproliferative effects and enhancement of the growth inhibitory action of 4-hydroxytamoxifen in estrogen receptor-positive breast cancer cell line.
    Paiva AM, Sousa ME, Camões A, Nascimento MSJ, Pinto MMM.
    Med Chem. Res 21(5): 552-558. 2012

  • Synthesis of a natural chalcone and its prenylated analogues – evaluation of tumor cell growth inhibitory activity and effects on cell cycle and apoptosis.
    Neves MP, Lima RT, Choosang K, Pakkong P, Nascimento MSJ, Vasconcelos MH, Pinto M, Silva AMS, Cidade H.
    Chem. Biodivers 9: (6 ): 1133-1143. 2012

  • Effects of a prenyl-baicalein derivative on ER (+) MCF-7 and ER (-) MDA-MB231 breast tumor cell lines.
    Neves MP, Cidade H, Pinto M, Silva AMS, Gales L, Damas AM, Lima RT, Vasconcelos MH, Nascimento MSJ
    Med. Chem. Res 21 (10):3154-3160. 2012

  • Virus hazards from food, water and other contaminated environments.
    Rodríguez-Lázaro D, Cook N, Ruggeri FM, Sellwood J, Nasser A, Nascimento MS, D'Agostino M, Santos R, Saiz JC, Rzeżutka A, Bosch A, Gironés R, Carducci A, Muscillo M, Kovač K, Diez-Valcarce M, Vantarakis A, von Bonsdorff CH, de Roda Husman AM, Hernández M, van der Poel WH
    FEMS Microbiol Rev. 36 (4) 786-814. 2012

  • Prevalence and transmission of hepatitis E virus in domestic swine populations in different European countries.
    Berto A, Baker JA, Mesquita JR, Nascimento MSJ, Banks M, Martelli F, Ostanello F, Angeloni G, Ruggeri FM, Bartolo I, Vasickova P, Diez-Valcarce M, Hernandez M, Rodriguez-Lazaro D, van der Poel WHM.
    BMC Research Notes 5: 190. 2012

  • Detection and characterization of hepatitis E virus in domestic pigs of different ages in Portugal.
    Berto A, Mesquita JR, Hakze-van der Honing R, Nascimento MSJ, van der Poel WH
    Zoonoses and Public Health 59, (7) 477–481. 2012

  • Molecular epidemiology of canine norovirus in dogs from Portugal, 2007-2011.
    Mesquita JR, Nascimento MS. (2012)
    BMC Vet Res. 8(1):107.

  • Favipiravir (T-705) inhibits in vitro norovirus replication.
    Rocha-Pereira J, Jochmans D, Dallmeier K, Leyssen P, Nascimento MSJ, Neyts J.
    Biochem Biophys Res Commun. 424 (4): 777-780. 2012

  • Serosurvey of veterinary conference participants for evidence of zoonotic exposure to canine norovirus - study protocol.
    Mesquita JR, Nascimento MSJ
    Virology Journal. 9 :250. 2012

  • Inhibition of norovirus replication by the nucleoside analogue 2’-C-methylcytidine.
    Rocha-Pereira J, Jochmans D, Dallmeier K, Leyssen P, Cunha R, Costa I, Nascimento MSJ, Neyts J
    Biochem Biophys Res Commun. 427(4): 796-800. 2012

  • Production and purification of the VP1 capsid protein of a novel canine norovirus using the Saccharomyces cerevisiae expression system.
    Pereira C, Lopes E, Mesquita JR, Nascimento MSJ, Saraiva L.
    Journal Microbiological Methods, 91 (3) 358-360. 2012

  • Comparison of Etest and a rapid flow cytometry-based method with the reference CLSI broth microdilution protocol M37-A3 for echinocandin susceptibility testing of Candida spp.
    Vale-Silva LA, Pinto P, Lopes V, Ramos H, Pinto E.
    Eur J Clin Microbiol, 31(6):941-6. 2012

  • Correlation of the chemical composition of essential oils from Origanum vulgare subsp. virens with the in vitro activity against clinical yeast and filamentous fungi.
    Vale-Silva LA, Silva M-J, Oliveira D, Gonçalves M-J, Cavaleiro C, Salgueiro L, Pinto E.
    J Med Microbiol, 61(1):252-60. 2012

  • Antifungal activity of phenolic rich Lavandula multifida L. essential oil.
    Zuzarte M, Vale-Silva L, Gonçalves MJ, Cavaleiro C, Canhoto J, Vaz S, Pinto E, Salgueiro L.
    Eur J Clin Microbiol, 31(7):1359-66. 2012

  • Azole resistance by loss of function of the sterol Δ5,6-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulence.
    Vale-Silva LA, Coste AT, Ischer F, Parker JE, Kelly SL, Pinto E, Sanglard D.
    Antimicrob Agents Ch, 56(4):1960-8. 2012

  • Can phlorotannins purified extracts constitute a novel pharmacological alternative for microbial infections with associated inflammatory conditions?
    Lopes G, Sousa C, Silva LR, Pinto E, Andrade PB, Bernardo J, Mouga T, Valentão P.
    PLOS ONE, 7(2):e31145. 2012

  • Aminodi(hetero)arylamines in the thieno[3,2-b]pyridines series: synthesis, effects in human tumor cells growth, cell cycle analysis, apoptosis and evaluation of toxicity using non-tumor cells.
    Calhelha RC, Ferreira ICFR, Peixoto D, Abreu RMV, Vale-Silva LA, Pinto E, Lima RT, Alvelos MI, Vasconcelos MH, Queiroz MJRP.
    Molecules, 17:3834-43. 2012

  • Beauveria bassiana keratitis in bullous keratopathy: antifungal sensitivity testing and management.
    Figueira L, Pinheiro D, Moreira R, Pinto E, Simões J, Camisa E, Torrão L, Palmares J, Falcão-Reis F.
    Eur J Ophthalmol, 22(5):814-818. 2012

  • New potential antitumoral di(hetero)arylether derivatives in the thieno[3,2-b]pyridine series: synthesis and fluorescence studies in solution and in nanoliposomes.
    Queiroz MJRP, Dias S, Peixoto D, Rodrigues ARO, Oliveira ADS, Coutinho PJG, Vale-Silva LA, Pinto E, Castanheira EMS.
    J Photoch Photobio A, 238:71-80. 2012

  • Interaction of antitumoral fluorescent heteroaromatic compounds, a benzothienopyrrole and two thienoindoles, with DNA and lipid membranes.
    Abreu AS, Castanheira EMS, Coutinho PJG, Queiroz MJRP, Ferreira PMT, Vale-Silva LA, Pinto E. J
    Photoch Photobio A, 240:14-25. 2012

  • Lavandula luisieri essential oil as a source of antifungal drugs.
    Zuzarte M, Gonçalves MJ, Cruz MT, Cavaleiro C, Canhoto J, Vaz S, Pinto E, Salgueiro L.
    Food Chem, 135(3):1505-10. 2012

2011
  • Cnidarians as a source of new marine bioactive compounds-an overview of the last decade and future steps for bioprospecting.
    Rocha J, Peixe L, Gomes NC, Calado R.
    Mar Drugs. 9(10):1860-86. 2011

  • Leakage of emerging clinically relevant multidrug-resistant Salmonella clones from pig farms.
    Antunes P, Mourão J, Pestana N, Peixe L.
    J Antimicrob Chemother. 66(9):2028-32. 2011

  • Non-susceptibility to tigecycline in enterococci from hospitalised patients, food products and community sources.
    Freitas AR, Novais C, Correia R, Monteiro M, Coque TM, Peixe L.
    Int J Antimicrob Agents. 38(2):174-6. 2011

  • First description of qnrS1-IncN plasmid in a ST11 Salmonella Enteritidis clinical isolate from Portugal.
    Antunes P, Mourão J, Machado J, Peixe L.
    Diagn Microbiol Infect Dis. Apr;69(4):463-5. 2011

  • Understanding the dynamics of imipenem-resistant Acinetobacter baumannii lineages within Portugal.
    Grosso F, Quinteira S, Peixe L.
    Clin Microbiol Infect. 17(8):1275-9. 2011

  • Unraveling Cyanobacteria Ecology in Wastewater Treatment Plants (WWTP).
    Martins J, Peixe L, Vasconcelos VM.
    Microb Ecol. 62(2):241-56. 2011

  • Human and Swine Hosts Share Vancomycin-Resistant Enterococcus faecium CC17, CC5, and Enterococcus faecalis CC2 Clonal Clusters Harboring Tn1546 on indistinguishable plasmids.
    Freitas AR, Coque TM, Novais C, Hammerum AM, Lester CH, Zervos MJ, Donabedian S, Jensen LB, Francia MV, Baquero F, Peixe L.
    J Clin Microbiol. 49(3):925-31. 2011

  • Characterization of the novel CMT enzyme TEM-154.
    Robin F, Delmas J, Machado E, Bouchon B, Peixe L, Bonnet R.
    Antimicrob Agents Chemother. 2011; 55(3):1262-5.

  • Characterization of antibiotic resistant enterococci isolated from untreated waters for human consumption in Portugal.
    Macedo AS, Freitas AR, Abreu C, Machado E, Peixe L, Sousa JC, Novais C.
    Int J Food Microbiol. 145(1):315-9. 2011

  • Optimization of processing conditions for the quantification of enterococci biofilms using microtitre-plates.
    Extremina CI, Costa L, Aguiar AI, Peixe L, Fonseca AP.
    J Microbiol Methods. 84(2):167-73. 2011

  • OXA-23-producing Acinetobacter baumannii: a new hotspot of diversity in Rio de Janeiro?
    Grosso F, Carvalho KR, Quinteira S, Ramos A, Carvalho-Assef AP, Asensi MD, Peixe L.
    J Antimicrob Chemother. 66(1):62-5. 2011

  • Leakage of emerging clinically relevant multidrug-resistant Salmonella clones from pig farms.
    Antunes P, Mourão J, Pestana N, Peixe L.
    J Antimicrob Chemother. 66(9):2028-32. 2011
    doi: 10.1093/jac/dkr228

  • Antifungal activity of xanthones: Evaluation of their effect on ergosterol biosynthesis by high-performance liquid chromatography.
    Pinto E, Afonso C, Duarte S, Vale-Silva L, Costa E, Sousa E, Pinto M.
    Chem Biol Drug Des, 77(3):212-22. 2011

  • Aspergillus viridinutans: an agent of adult chronic invasive aspergillosis.
    Coelho D, Silva S, Vale-Silva L, Gomes H, Pinto E, Sarmento A, Pinheiro MD.
    Med Mycol, 49(7):755-9. 2011

  • Chemical composition and antifungal activity of the essential oils of Lavandula viridis L´Hér.
    Zuzarte M, Gonçalves MJ, Cavaleiro C, Canhoto J, Vale-Silva L, Silva MJ, Pinto E, Salgueiro L. J
    Med Microbiol, 60(5):612-8. 2011

  • Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate.
    Abreu AS, Castanheira EMS, Queiroz MJRP, Ferreira PMT, Vale-Silva LA, Pinto E.
    Nanoscale Res Lett, 6(1):482-7. 2011

  • Evaluation of Effect of Triterpenes and Limonoids on Cell Growth, Cell Cycle and Apoptosis in human tumor cell lines.
    Cazal CM, Choosang K, Severino VG, Soares MS, Sarria AL, Fernandes JB, Silva MF, Vieira PC, Pakkong P, Almeida GM, Vasconcelos MH, Nascimento MS, Pinto MM.
    Anticancer Agents Med Chem. (in press)

  • Simultaneous targeting of P-gp and XIAP with siRNAs increases sensitivity of P-gp overexpressing CML cells to Imatinib.
    Seca H, Lima RT, Guimarães JE, Vasconcelos MH.
    Hematology. (in press)

  • The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation.
    Gazanion E, Garcia D, Silvestre R, Gérard C, Guichou JF, Labesse G, Seveno M, Cordeiro-Da-Silva A, Ouaissi A, Sereno D, Vergnes B.
    Mol Microbiol. Oct; 82(1):21-38. 2011

  • P-glycoprotein activity in human Caucasian male lymphocytes does not follow its increased expression during aging.
    Vilas-Boas V, Silva R, Gaio AR, Martins AM, Lima SC, Cordeiro-da-Silva A, de Lourdes Bastos M, Remião F.
    Cytometry A. Nov; 79(11):912-9. 2011

  • Seroepidemiological survey of Leishmania infantum infection in dogs from northeastern Portugal.
    Sousa S, Lopes AP, Cardoso L, Silvestre R, Schallig H, Reed SG, Cordeiro da Silva A. 2011 Acta Trop. Oct-Nov; 120(1-2):82-7. 2011

  • Proinflammatory environment dictates the IL-17-producing capacity of human invariant NKT cells.
    Moreira-Teixeira L, Resende M, Coffre M, Devergne O, Herbeuval JP, Hermine O, Schneider E, Rogge L, Ruemmele FM, Dy M, Cordeiro-da-Silva A, Leite-de-Moraes MC.
    J Immunol. May 15;186(10):5758-65. 2011

  • Leakage of emerging clinically relevant multidrug-resistant Salmonella clones from pig farms.
    Antunes P, Mourão J, Pestana N, Peixe L.
    J Antimicrob Chemother. 2011 Jun 22.

  • Non-susceptibility to tigecycline in enterococci from hospitalized patients, food products and community sources.
    Freitas AR., Novais C., Correia R., Monteiro M., Coque TM, Peixe L.
    International Journal of Antimicrobial Agents. 2011; 38(2):174-6

  • First description of qnrS1-IncN plasmid in a ST11 Salmonella Enteritidis clinical isolate from Portugal.
    Antunes P, Mourão J, Machado J, Peixe L.
    Diagn Microbiol Infect Dis. 2011 Apr;69(4):463-5.

  • Understanding the dynamics of imipenem-resistant Acinetobacter baumannii lineages within Portugal.
    Grosso F, Quinteira S, Peixe L.
    Clin Microbiol Infect. 2011 Jan 24. doi: 10.1111/j.1469-0691.2011.03469.x.

  • Human and Swine Hosts Share Vancomycin-Resistant Enterococcus faecium CC17, CC5, and Enterococcus faecalis CC2 Clonal Clusters Harboring Tn1546 on indistinguishable plasmids.
    Freitas AR, Coque TM, Novais C, Hammerum AM, Lester CH, Zervos MJ, Donabedian S, Jensen LB, Francia MV, Baquero F, Peixe L.
    J Clin Microbiol. 2011 Mar;49(3):925-31

  • Characterization of antibiotic resistant enterococci isolated from untreated waters for human consumption in Portugal.
    Macedo AS, Freitas AR, Abreu C, Machado E, Peixe L, Sousa JC, Novais C.
    Int J Food Microbiol. 145(1):315-9. 2011

  • OXA-23-producing Acinetobacter baumannii: a new hotspot of diversity in Rio de Janeiro?
    Grosso F, Carvalho KR, Quinteira S, Ramos A, Carvalho-Assef AP, Asensi MD, Peixe L.
    J Antimicrob Chemother. 66(1):62-5. 2011

  • Cnidarians as a source of new marine drugs - most promising compounds in the 21st century and future steps for bioprospecting
    Rocha J., Peixe L., Gomes N., Calado R.
    WCMB. 2011

  • Unraveling Cyanobacteria Ecology in Wastewater Treatment Plants (WWTP).
    Martins J, Peixe L, Vasconcelos VM.
    Microb Ecol. Feb 2. 2011

  • MicroRNA regulation of core apoptosis pathways in cancer.
    Lima RT, Busacca S, Almeida GM, Gaudino G, Fennell DA, Vasconcelos MH.
    Eur J Cancer. 47: 163-74. 2011

  • Synthesis and evaluation of tumor cell growth inhibition of methyl 3-amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure-activity relationships, effects on the cell cycle and apoptosis.
    Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Almeida GM, Vasconcelos MH
    Eur J Med Chem46: 236-40. 2011

  • Chemical composition of wild edible mushrooms and antioxidant properties of their water soluble polysaccharidic and ethanolic fractions.
    VazJA, Barros L, Martins A, Santos-Buelga C, Vasconcelos MH, Ferreira IC
    Food Chemistry, 126: 610-16. 2011

  • EBV interferes with the sensitivity of Burkitt Lymphoma Akata cells to etoposide.
    Lima RT, Seca H, Soares P, Nascimento MSJ, Vasconcelos MH
    J Cell Biochem, 112:200-10. 2011

  • Phenolic profile of seventeen Portuguese wild mushrooms.
    Vaz JA, Barros L, Martins A, Morais JS, Vasconcelos MH, Ferreira ICFR
    LWT - Food Science and Technology, 44: 343-346. 2011

2010
  • Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: Synthesis and antitumoral activities.
    Queirós MJRP, Calhelha RC, Vale-Silva LA, Pinto E, Nascimento
    MSJ. Eur J Med Chem, 45(12):5732-8. 2010

  • Activation of hosphatidylinositol 3-kinase/Akt and impairment of nuclear factor-kappaB: molecular mechanisms behind the arrested maturation/activation state of Leishmania infantum-infected dendritic cells.
    Neves BM, Silvestre R, Resende M, Ouaissi A, Cunha J, Tavares J, Loureiro I, Santarém N, Silva AM, Lopes MC, Cruz MT, Cordeiro da Silva A.
    Am J Pathol. Dec;177(6):2898-911. 2010

  • In vitro and in vivo anticancer activity of a novel nano-sized formulation based on self-assembling polymers against pancreatic cancer.
    Hoskins C, Ouaissi M, Lima SC, Cheng WP, Loureirio I, Mas E, Lombardo D, Cordeiro-da-Silva A, Ouaissi A, Kong Thoo Lin P.
    Pharm Res. Dec;27(12):2694-703. 2010

  • In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells.
    Silva R, Carmo H, Dinis-Oliveira R, Cordeiro-da-Silva A, Lima SC, Carvalho F, de Lourdes Bastos M, Remião F.
    Arch Toxicol. Sep 21. 2010

  • Application of an improved enzyme-linked immunosorbent assay method for serological diagnosis of canine leishmaniasis.
    Santarém N, Silvestre R, Cardoso L, Schallig H, Reed SG, Cordeiro-da-Silva A.
    J Clin Microbiol. May;48(5):1866-74. 2010

  • Bisnaphthalimidopropyl derivatives as inhibitors of Leishmania SIR2 related protein 1.
    Tavares J, Ouaissi A, Kong Thoo Lin P, Loureiro I, Kaur S, Roy N, Cordeiro-da-Silva A.
    ChemMedChem. Jan;5(1):140-7. 2010

  • Characterization of the novel CMT enzyme TEM-154.
    Robin F, Delmas J, Machado E, Bouchon B, Peixe L, Bonnet R.
    Antimicrob Agents Chemother. 2010 [Epub ahead of print]

  • Emergence of an IncIg plasmid encoding CMY-2 ß -lactamase associated with the international ST19 OXA-30-producing ß-lactamase Salmonella Typhimurium multidrug-resistant clone.
    Antunes P, Coque TM, Peixe L.
    J Antimicrob Chemother.65(10):2097-100. 2010

  • Global spread of the hyl(Efm) colonization-virulence gene in megaplasmids of the Enterococcus faecium CC17 polyclonal subcluster.
    Freitas AR, Tedim AP, Novais C, Ruiz-Garbajosa P, Werner G, Laverde-Gomez JA, Cantón R, Peixe L, Baquero F, Coque TM.
    Antimicrob Agents Chemother. 54(6):2660-5. 2010

  • Emergence of an extreme-drug-resistant (XDR) Acinetobacter baumannii carrying blaOXA-23 in a patient with acute necrohaemorrhagic pancreatitis.
    Grosso F, Quinteira S, Peixe L.
    J Hosp Infect. 75(1):82-3. 2010

  • International spread and persistence of TEM-24 is caused by the confluence of highly penetrating enterobacteriaceae clones and an IncA/C2 plasmid containing Tn1696::Tn1 and IS5075-Tn21.
    Novais A, Baquero F, Machado E, Cantón R, Peixe L, Coque TM.
    Antimicrob Agents Chemother.54(2):825-34. 2010

  • Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle.
    Queirós MJRP, Calhelha RC, Vale-Silva LA, Pinto E, Lima RT, Vasconcelos MH
    Eur J Med Chem 45: 5628-5634. 2010

  • The in vitro anticancer activity of the crude extract of the sponge-associated fungus Eurotium cristatum and its secondary metabolites.
    Almeida AP, Dethoup T, Singburaudom N, Lima R, Vasconcelos MH, Pinto M, Kijjoa A
    J Nat Pharm, 1 (1): 25-29. 2010

  • Wild mushrooms Clitocybe alexandri and Lepista inversa: In vitro antioxidant activity and growth inhibition of human tumour cell lines.
    Vaz JA, Heleno SA, Martins A, Almeida GM, Vasconcelos MH, Ferreira ICF
    Food Chem Toxicol, 48: 2881-2884. 2010

  • Compounds from wild mushrooms with antitumor potential.
    Ferreira IC, Vaz JA, Vasconcelos MH, Martins A
    Anticancer Agents Med Chem, 10(5):424-36. 2010

  • Insights into the in vitro antitumor mechanism of action of a new pyranoxanthone.
    Palmeira A, Paiva A, Sousa E, Seca H, Almeida GM, Lima RT, Fernandes MX, Pinto M, Vasconcelos MH
    Chem Biol Drug Des, 76:43-58. 2010

  • miR signatures and the role of miRs in acute myeloid leukaemia.
    Seca H, Almeida GM, Guimarães JE, Vasconcelos MH
    Eur J Cancer, 46(9):1520-7. 2010

  • Antifungal activity of the essential oil of Thymus x viciosoi against Candida, Cryptococcus, Aspergillus and dermatophyte species.
    Vale-Silva LA, Gonçalves MJ, Cavaleiro C, Salgueiro L, Pinto E
    Planta Medica, 76: 1-7. 2010

  • Lycopersicon esculentum seeds: an industrial byproduct as an antimicrobial agent.
    Taveira M, Silva LR, Vale-Silva LA, Pinto E, Valentão P, Ferreres F, Pinho PG, Andrade PB
    J. Agric. Food Chem., 58: 9529-9536. 2010

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