Organic Chemistry II

Code:

MI071209

Acronym:

QORG2

Keywords
Classification	Keyword
OFICIAL	Physical Sciences

Instance: 2012/2013 - 2S

Active?	Yes
Responsible unit:	Organic and Pharmaceutical Chemistry Laboratory
Course/CS Responsible:	MSc in Pharmaceutical Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MICF	563	Official Curriculum	1	-	7	65	189

Teaching language

Portuguese

Objectives

a) Understanding the behaviour of carbon compounds and the modulation of this behaviour by the introduction of chemical functions. Systematisation of the different families of organic compounds and their associated behaviour. Relationship between the different organic families. Understanding the importance of tri-dimensionality of organic structures. Understanding the existence of the structure – chemical behaviour relationship. Chemicals synthesis, reactivity and characteristic reactions of several families of organic compounds. Acquisition of basic experimental methodology used in clarifying structure, either by chemical or spectrometric means. Evolution of student competence in the laboratory, developing good practices in the use of material and equipment while at the same time acquiring a greater awareness of laboratory safety rules. b) A basic knowledge of Organic Chemistry from the Organic Chemistry I subject is assumed. The presence and constant revision of this knowledge during the Organic Chemistry II subject is recommended.

Learning outcomes and competences

To understand and to predict the behavior of organic substances: their reactivity, synthesis, physicochemical characteristics. Given the structure of a substance, knowing to predict the UV, IR, NMR and MS spectra characteristics. Given the UV, IR, NMR and MS spectra of a substance, knowing to propose compatible structures.

To propose a protocol leading to the identification of an unknown substance.

Autonomy in the implementation of organic chemistry laboratory protocols (assessment of purity, purification, and identification of unknown pure substances and chemical extraction

Working method

Presencial

Program

Systematic identification of organic compounds. Application of the spectrometric methods in structural determination, with special relevance to spectrophotometry in UV, IR, NMR and MS. Detection and confirmation of functional groups by chemical and spectral based methods. Study of functional organic compounds (alcohols, thiols, ethers, aldehydes and ketones, carboxylic acids and derivatives, enols, phenols, alkylamines and arylamines): nomenclature, physical - chemical properties, spectroscopic properties, preparation processes, properties and reactivity and mechanisms. Resolution of mixtures by chemical means.

Mandatory literature

McMurry John; Organic chemistry. ISBN: 0-534-42005-2
Shriner Ralph L. 070; systematic identification of organic compounds. ISBN: 0-471-21503-1
Ault Addison; Techniques and experiments for organic chemistry. ISBN: 0-205-06528-7
Vollhardt K. Peter C.; Organic chemistry: structure and function. ISBN: 0-7167-2721-8
Solomons T. W. Graham; Organic chemistry. ISBN: 0-471-03594-7
J. Pasto Daniel; Determinación de estructuras orgánicas
Pecsok Robert L.; Métodos modernos de análisis químico

Teaching methods and learning activities

a) Theoretical classes (3 hours / week): Powerpoint presentations; associating the subject-matters taught with information and curiosities on the work of the chemicals discussed in the class and the way those subject-matters are related to day to day life. b) The laboratory work (2 hours / week, 12 weeks) is carried out in groups of 2 to 3 students on a rotary basis and according to a chronogram. The logic behind this and the objectives to attain are previously made known to the students. The lecturer responsible is available for student consultation at the hours specified in the beginning of the semester and by prior agreed appointment at any other time. c) The students are involved in bibliographical research tasks covering themes related to the subject-matters taught and their application. This work is on-going and is discussed with the participants over the semester. The professors involved in the theoretical and laboratorial classes are available to discuss any doubts raised by the students either by direct contact in the scheduled period made known to students at the beginning of the semester or by email contact.

Software

ChemBioOffice 2010
Chime, MDL® - gratuito em http://www.mdli.com/downloads/)
ACD/ChemSketch Freeware gratuito em: http://www.acdlabs.com/resources/freeware/chemsketch/
Chime, MDL® - gratuito em: http://www.umass.edu/microbio/chime/getchime.htm/)

keywords

Physical sciences > Chemistry > Organic chemistry > Quimica do carbono

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
Attendance (estimated)	Participação presencial	85,00	10,00
250	Exame	32,00	90,00
	Total:	-	100,00

Eligibility for exams

- Student attendance to the Laboratory classes is mandatory. Those students whose attendance is lower than 3/4 of the classes effectively taught are considered as without attendance, as long as these classes represent more than 50% of the classes predicted. Nevertheless, at the end of the classes period the student must have performed all the laboratorial tasks foreseen in the laboratorial program. - Attendance to Theoretical classes is not compulsory.

Calculation formula of final grade

The evaluation to be carried out in the laboratory classes will encompass the students´ performance of as well as the improvement in their capabilities and the comprehension of the contents taught in the discipline. These aspects will account for 2 values in the final classification (0-20). This evaluation might include the appreciation of the student’s proficiency and answering oral or written questions on any aspect (practical or theoretical) related to the understanding of the work being performed. The students should prepare a report for each laboratorial task, accounting for 1 value in the final classification, and deliver it in the following class. Roughly at half the semester, the students will be submitted to a follow-up evaluation test including both the theoretical and laboratorial contents taught until then. This component will account for 5 values to the final classification. The final written exam performed during the normal exams period will encompass all the contents (laboratorial and theoretical) lectured during the semester will special focus on their inter-linkage. It will account for 12 values to the final classification. Summing up, the evaluation is distributed as follows: - Laboratorial performance, comprehension of underlying fundamentals and reports (15%) - Intermediate written test (25%) - Final exam (60%) Those students achieving 9,5 or a higher classification are considered as approved. Those student awarded a classification under 8,5 fail approval. Those studends achieving a classification between 8,5 and 9,5 shall be submitted to an oral evaluation in order to confirm their competence.

Examinations or Special Assignments

Laboratorial evaluation: performance, comprehension of the taught contents and reports. Intermediate written test devoted to assess the students learning status regarding both the theoretical and laboratorial contents.

Special assessment (TE, DA, ...)

The legal approved "Normas de Avaliação” are applied. The exams for the special regime students are carried out in accordance with that established in the applicable legislation for each specific situation.

Classification improvement

The legal approved "Normas de Avaliação” are applied. - The student has the right to request the repeat of the final test to improve the mark in the in one of the normal or resource period of the following academic year in which he/she carried out the test . - The repeat of the tests to improve the mark can be undertaken only once per subject. - The final subject classification will be the higher of those obtained in the two tests carried out. The classification improvement in Química Orgânica II is obtained through a written exam including all contents taught in the subject, both theoretical and laboratorial.

Observations

Basic knowledges aquired in Química Orgânica I are very important. This knowledge is assumed as students´ chemical background when lecturing the Química Organica II subject matters.