Resumo (PT):
In this work, the construction and performance evaluation of PVC membranes ion-selective electrodes for the determination of tetracycline type antibiotics is described. Electrodes with the best responses were based on plastic membranes containing 31% (w/w) PVC, 68% (w/w) of dibutylphthalate as plasticizer and 1% (w/w) of β-cyclodextrin as ionophore. The electrodes were responsive over 6 months to tetracycline, oxytetracycline, doxycycline and chlortetracycline in glycine buffer solution (pH 2), in the dynamic range 2×10−5–10−2 mol L−1 with a constant slope of about 55 mV/dec To enable large scale analysis reducing wastes as associated costs tubular shape electrodes were coupled to a sequential-injection analysis system and its performance evaluated using pharmaceutical samples and waste waters from a treatment facility. The sample throughput of 51 samples h−1 was enabled by the system as well as results that favorably agree with those provided by chromatographic analysis
<br>
<br>
Keywords:Tetracyclines;Waste water analysis;Potentiometric sensors;Cyclodextrins
<br>
<a target="_blank" href="http://onlinelibrary.wiley.com/doi/10.1002/elan.201000301/abstract "> Texto integral </a>
<br>
<br>
Abstract (EN):
In this work, the construction and performance evaluation of PVC membranes ion-selective electrodes for the determination of tetracycline type antibiotics is described. Electrodes with the best responses were based on plastic membranes containing 31% (w/w) PVC, 68% (w/w) of dibutylphthalate as plasticizer and 1% (w/w) of beta-cyclodextrin as ionophore. The electrodes were responsive over 6 months to tetracycline, oxytetracycline, doxycycline and chlortetracycline in glycine buffer solution (pH 2), in the dynamic range 2 x 10(-5)-10(-2) mol L-1 with a constant slope of about 55 mV/dec To enable large scale analysis reducing wastes as associated costs tubular shape electrodes were coupled to a sequential-injection analysis system and its performance evaluated using pharmaceutical samples and waste waters from a treatment facility. The sample throughput of 51 samples h(-1) was enabled by the system as well as results that favorably agree with those provided by chromatographic analysis.
Idioma:
Inglês
Tipo (Avaliação Docente):
Científica
Nº de páginas:
6