Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2021

Autores

Petit, RG (Autor) Outra; Cano, A (Autor) Outra; Ortiz, A (Autor) Outra; Espina, M (Autor) Outra; Prat, J (Autor) Outra; Munoz, M (Autor) Outra; Severino, P (Autor) Outra; Souto, EB (Autor) Outra; Garcia, ML (Autor) Outra; Pujol, M (Autor) Outra; Sanchez Lopez, E (Autor) Outra

Revista

Título: International Journal Of Molecular Sciences

Vol. 22 Nº 9

Página Final: 4983

ISSN: 1661-6596

Editora: MDPI

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Classificação Científica

CORDIS: Ciências da Saúde

Outras Informações

ID Authenticus: P-00T-XD0

DOI: 10.3390/ijms22094983

Abstract (EN): Research in the pathogenesis of inflammatory skin diseases, such as skin dermatitis and psoriasis, has experienced some relevant breakthroughs in recent years. The understanding of age-related factors, gender, and genetic predisposition of these multifactorial diseases has been instrumental for the development of new pharmacological and technological treatment approaches. In this review, we discuss the molecular mechanisms behind the pathological features of psoriasis, also addressing the currently available treatments and novel therapies that are under clinical trials. Innovative therapies developed over the last 10 years have been researched. In this area, advantages of nanotechnological approaches to provide an effective drug concentration in the disease site are highlighted, together with microneedles as innovative candidates for drug delivery systems in psoriasis and other inflammatory chronic skin diseases.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 25