The effects of surface properties on escherichia coli adhesion are modulated by shear stress

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

J. M. R. Moreira (Autor) FEUP; J. D. P. Araújo (Autor) FEUP; J. M. Miranda (Autor) FEUP; M. Simões (Autor) FEUP; L. F. Melo (Autor) FEUP; F. J. Mergulhão (Autor) FEUP

Revista

Título: Colloids and Surfaces B: Biointerfaces

Vol. 123

Páginas: 1-7

ISSN: 0927-7765

Editora: Elsevier

Indexação

ISI Web of Knowledge - 15 Citações

ISI Web of Science

Scopus - 26 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias

CORDIS: Ciências Tecnológicas

Projetos Associados

Filmstart - Estudo das condições iniciais que controlam a formação de biofilmes

PTDC/EQU-FTT/105535/2008 - Sujamento e limpeza de micro canais

Outras Informações

ID Authenticus: P-009-XAJ

DOI: 10.1016/j.colsurfb.2014.08.016

Abstract (EN): The adhesion of Escherichia colito glass and polydimethylsiloxane (PDMS) at different flow rates (between 1 and 10 ml s−1) was monitored in a parallel plate flow chamber in order to understand the effect of surface properties and hydrodynamic conditions on adhesion. Computational fluid dynamics was used to assess the applicability of this flow chamber in the simulation of the hydrodynamics of relevant biomedical systems. Wall shear stresses between 0.005 and 0.07 Pa were obtained and these are similar to those found in the circulatory, reproductive and urinary systems. Results demonstrate that E. coli adhesion to hydrophobic PDMS and hydrophilic glass surfaces is modulated by shear stress with surface properties having a stronger effect at the lower and highest flow rates tested and with negligible effects at intermediate flow rates. These findings suggestthat when expensive materials or coatings are selected to produce biomedical devices, this choice should take into account the physiological hydrodynamic conditions that will occur during the utilization of those devices.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7