Obesity and metabolic syndrome in 7-9 years-old Portuguese schoolchildren

• Tipo: Artigo em Revista Científica Internacional
• Data: 2010

Autores

Almeida, Maria Daniel Vaz de (Autor) FCNAUP; Correia, Flora (Autor) FCNAUP; Oliveira, Bruno M. P. (Autor) FCNAUP; Albuquerque, Isabel (Autor) FCNAUP; Simões-Pereira, Carlos (Autor) FCNAUP

Revista

Título: Diabetology and Metabolic Syndrome

Vol. 2 Nº 1

Página Inicial: 40

ISSN: 1758-5996

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 21 Citações

Scopus - 24 Citações

Pubmed / Medline

Classificação Científica

FOS: Ciências médicas e da saúde > Ciências da saúde

CORDIS: Ciências da Saúde > Ciências Médicas > Medicina > Pediatria

Outras Informações

ID Authenticus: P-003-5RB

DOI: 10.1186/1758-5996-2-40

Abstract (EN): Background: Body fat is related to changes in lipid profile, blood pressure and metabolism of insulin and glucose, known as the metabolic syndrome (MS). The aim of this study was to estimate the prevalence of metabolic syndrome (MS) and its components among overweight and obese Portuguese schoolchildren, and to identify associated clinical and biochemical characteristics. Methods: A total of 82 children (14 overweight and 68 obese; 40 boys and 42 girls) aged 7-9 years, underwent anthropometric measurements. A blood sample was obtained to assess biochemical parameters. Insulin resistance (IR) was determined by the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). MS was defined by the National Cholesterol Education Program Adult Treatment Panel III criteria modified by Cook. Results: The prevalence of MS was 15.8%. Abdominal obesity was present in all children. Frequency of elevated blood pressure, low HDL-cholesterol and elevated triglyceride concentrations were 62.6%, 13.4% and 11.0%, respectively. None of the children presented impaired fasting glucose, however hyperinsulinemia (7.3%) and IR (8.5%) were observed. The number of components of MS was higher in children with higher z-BMI (ρ = 0.411; p < 0.001). MS was associated with higher leptin concentrations. No association was found with adiponectin or ghrelin levels. Leptin correlated positively with obesity, glucose metabolism, lipid profile, hepatic function and C-reactive protein, and negatively with HDL and Apolipoprotein A-I/B ratio. Conclusions: This study shows a significant prevalence of MS among obese schoolchildren. Abdominal obesity and elevated blood pressure were the most frequent components of this syndrome. Dyslipidemia, IR and high levels of leptin were also associated with MS in this young group.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Notas: <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=20537155[pmid]">Indexado na PubMed</a>

Nº de páginas: 7