Structural analysis of three methyl N-phosphorylated 5,6-dihydroxy-2-azabicyclo[2.2.1]heptane-3-carboxylates

• Tipo: Artigo em Revista Científica Internacional
• Data: 2012

Autores

Carlos A D Sousa (Autor) Outra; Luisa L C Vale (Autor) FCUP; Jose E Rodriguez Borges (Autor) FCUP; Xerardo Garcia Mera (Autor) Outra

Revista

Título: Journal of Molecular Structure

Vol. 1007

Páginas: 31-35

ISSN: 0022-2860

Editora: Elsevier

Indexação

ISI Web of Knowledge - 2 Citações

Scopus - 2 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-002-DY5

DOI: 10.1016/j.molstruc.2011.09.041

Abstract (EN): Both exo and endo isomers of (+/-)-methyl N-diphenylphosphoryl-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate and (+/-)-methyl N-diphenylphosphoryloxy-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate were dihydroxylated with OsO4. The unexpected formation of (+/-)-methyl 5,6-dihydroxy-N-diphenylphosphoryl-2-azabicyclo[2.2.1]heptane-3-endo-carboxylate from (+/-)-methyl N-diphenylphosphoryloxy-2-azabicyclo[2.2.1]hept-5-ene-3-endo-carboxylate is discussed based on NMR analyses and experimental observations. The two N-diphenylphosphoryl dihydroxybicycles are analyzed in terms of their crystalline structure by X-ray crystallography.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5