Code: | M.BIO038 | Acronym: | EMB |
Keywords | |
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Classification | Keyword |
OFICIAL | Molecular Bioengineering |
Active? | Yes |
Responsible unit: | Department of Chemical and Biological Engineering |
Course/CS Responsible: | Master in Bioengineering |
Acronym | No. of Students | Study Plan | Curricular Years | Credits UCN | Credits ECTS | Contact hours | Total Time |
---|---|---|---|---|---|---|---|
M.BIO | 17 | Syllabus | 1 | - | 6 | 58,5 | 162 |
M.EQ | 9 | Syllabus | 2 | - | 6 | 58,5 | 162 |
To provide the students with the skills needed for the quantification of metabolic fluxes and the use of informatic tools for the analysis and simulations of metabolic processes.
-To understand the importance of metabolic engineering in modern bioengineering
-To know the main mathematical models for the analysis of metabolic and celular systems
-To develop skills in the biomathematics analysis of metabolic networks
-To develop skills in the biomathematical analysis of metabolic fluxes
-To acquire knowledge and develop skills in the use of databases in metabolic engineering
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-Metabolic engineering; Omics; System Biology; Synthetic Biology
Strategic approaches in metabolic engineering:
- Data analysis in protein-protein interaction
-Metabolic network and flux analysis
-Metabolic control analysis
- Tools for the subcellular localization of (macro)molecules
-Analytical methods for metabolic engineering
Databases in biotechnology
Emerging applications of metabolic engineering
Practical component - Bioinformatics:
-Introduction to bioinformatics
-Application of software in nucleic acid sequences analysis
-Generation of the metabolic stoichiometric matrix and metabolic flux calculation
-Use of databases in biotechnology (data mining) and computational tools for metabolic engineering
-Quantitative prediction of cellular metabolism with constraints-based models
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Formal exposition of the theoretical and practical elements, using video projector and online material accessible via the Internet. Development of tutorial examples and problem solving with the use of appropriate software.
Designation | Weight (%) |
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Exame | 60,00 |
Trabalho prático ou de projeto | 40,00 |
Total: | 100,00 |
Designation | Time (hours) |
---|---|
Estudo autónomo | 80,00 |
Frequência das aulas | 70,00 |
Trabalho de investigação | 12,00 |
Total: | 162,00 |
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The final grade will be calculated according to the following components:
Final exam (60% in the final classification);
Oral presentation of one emerging theme in metabolic and cellular engineering and respective report (40% in the final classification).
Recurso exam.
To obtain positive rating, the student must obtain a minimum overall rating of 9.5. The grade of the final exam must be >8.
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These situations do not preclude the completion of the works proposed. These have to be performed at the same time limit established for regular students. The form of assessment is therefore the same for all students.
Recurso exam.
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