Code: | EBE0133 | Acronym: | PSBI |
Keywords | |
---|---|
Classification | Keyword |
OFICIAL | Biological Engineering |
Active? | Yes |
Responsible unit: | Department of Chemical Engineering |
Course/CS Responsible: | Master in Bioengineering |
Acronym | No. of Students | Study Plan | Curricular Years | Credits UCN | Credits ECTS | Contact hours | Total Time |
---|---|---|---|---|---|---|---|
MIB | 21 | Syllabus | 4 | - | 6 | 56 | 162 |
MIEQ | 17 | Syllabus | 4 | - | 6 | 56 | 162 |
5 |
To acquire advanced engineering knowledge in purification processes of biological products, as well as their approval and regulation. To develop students’ reasoning skills, as well as their capacity to analyse production diagrams and to use bioinformatic tools.
Learn how to analyze an industrial production process particularly the operation units concerning downstream processing. Learn how to select the most adequate equipment for each operation unit and to perform equipment sizing in particular cases.
1- Biotechnology and bioproducts 2- Introduction to the purification of biological products 3- Cell rupture a) Mechanical methods b) Non-mechanical methods 4- Solid-liquid separation a) Sedimentation b) Centrifugation c) Conventional filtration d) Membrane processes 5- Chromatography a) Gel filtration b) Ionic exchange c) Affinity d) Hydrophobic interaction 6- Extraction processes 7- Precipitation and crystallization 8- Solvent removal a) Drying b) Freeze drying c) Evaporation 9- Product activity 10- Regulation a) Validation b) Approval c) Formulation 11-Bioinformatic analysis of proteins 12- Analysis of production diagrams 13- Simulation of purification processes
Oral presentation with the support of the board and slides. Classes at the computer room using simulation software and bioinformatic tools available on the web.
Designation | Weight (%) |
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Trabalho escrito | 100,00 |
Total: | 100,00 |
According to General Evaluation Rules of FEUP, students have to attend classes.
Final grade will be obtained by an weighted average of the several components of the final work, the classification from the oral presentations and the log book. The respective weights wil be discussed on class.
Students will have to do a group assignment, being the assignment sheet delivered at the beginning of the semester. The assignment is to be carried out during the semester (some parts will be carried out in class). The group assignment comprises: a) Introduction b) Patent research c) Development of a production diagram d) Bioinformatic analysis of proteins e) Simulation of purification processes f) Conclusion. This work will be orally presented and discussed in class.
By globla exam on the resit period. Admittance to that exam requires the delivery of the group work with all its components and with a final evaluation of at least 7/20 points.
Students can improve their grades by attending an exam at the recurso (resit) season.