Automatic analysis of macroarrays images

• Type: Article in International Conference Proceedings Book
• Date: 2010

Authors

Caridade, CMR (Author) Other; Marcal, ARS (Author) FCUP; Mendonca, T (Author) FCUP; Albuquerque, P (Author) Other; Mendes, MV (Author) Other; Tavares, F (Author) Other

Conference proceedings International

Title: 2010 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)

Pages: 6122-6125

32nd Annual International Conference of the IEEE Engineering-in-Medicine-and-Biology-Society (EMBC 10)

Buenos Aires, ARGENTINA, AUG 30-SEP 04, 2010

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 6 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-003-D8A

DOI: 10.1109/iembs.2010.5627805

Abstract (EN): The analysis of dot blot (macroarray) images is currently based on the human identification of positive/negative dots, which is a subjective and time consuming process. This paper presents a system for the automatic analysis of dot blot images, using a pre-defined grid of markers, including a number of ON and OFF controls. The geometric deformations of the input image are corrected, and the individual markers detected, both tasks fully automatically. Based on a previous training stage, the probability for each marker to be ON is established. This information is provided together with quality parameters for training, noise and classification, allowing for a fully automatic evaluation of a dot blot image.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4