Recent advances on computational proteomics

• Type: Article in International Scientific Journal
• Date: 2009

Authors

Sousa, SF (Author) FCUP; Cerqueira, NMFSA (Author) FCUP; Perez, MAS (Author) Other; Moreira, IS (Author) Other; Ribeiro, AJM (Author) Other; Neves, ARAP (Author) Other; Ramos, MJ (Author) FCUP; Fernandes, PA (Author) FCUP

Journal

Title: World Academy of Science, Engineering and Technology

Vol. 56

Pages: 376-386

ISSN: 2010-376X

Publisher: World Academy of Science Engineering and Technology

Indexing

ISI Web of Knowledge

Scopus - 0 Citations

Other information

Authenticus ID: P-007-X1N

Abstract (EN): In this work we report the recent progresses that have been achieved by our group in the last half decade on the field of computational proteomics. Specifically, we discuss the application of Molecular Dynamics Simulations and Electronic Structure Calculations in drug design, in the clarification of the structural and dynamic properties of proteins and enzymes and in the understanding of the catalytic and inhibition mechanism of cancer-related enzymes. A set of examples illustrate the concepts and help to introduce the reader into this important and fast moving field.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 11