Abstract (EN):
This article describes an Excel based tool specifically designed to perform the life cycle assessment
(LCA) and the sustainability evaluation of pharmaceutical products and /or processes. In the current
state of development the tool deals with the case study of the production of a lyophilized product for
intravenous injection, with an active pharmaceutical ingredient (API) produced by fermentation using
genetically modified organisms. A gate-to-gate (GTG) analysis is done, considering the API production,
the final product formulation, its storage and distribution, and the auxiliary operations involved. These
steps are included in the aforementioned tool, and a set of sustainability indicators is proposed to make
a quantitative sustainability assessment of this pharmaceutical product and process, based on the
relevant impacts identified on its life cycle. Despite the limitations, the LCA and the sustainability
assessment tool presented here can be easily modified to other types of pharmaceutical processes,
given that good descriptions of them are available.
Language:
English
Type (Professor's evaluation):
Scientific
No. of pages:
6