From Ocean to Medicine: Pharmaceutical Applications of Metabolites from Marine Bacteria

• Type: Another Publication in an International Scientific Journal
• Date: 2020

Authors

Santos, JD (Author) Other; Vitorino, I (Author) Other; Reyes, F (Author) Other; Vicente, F (Author) Other; lage, om (Author) FCUP

Journal

Title: Antibiotics

Vol. 9 No. 5

Pages: 1-30

Publisher: MDPI

Indexing

ISI Web of Knowledge - 22 Citations

Scopus - 32 Citations

Other information

Authenticus ID: P-00S-J3C

DOI: 10.3390/antibiotics9080455

Abstract (EN): Oceans cover seventy percent of the planet's surface and besides being an immense reservoir of biological life, they serve as vital sources for human sustenance, tourism, transport and commerce. Yet, it is estimated by the National Oceanic and Atmospheric Administration (NOAA) that eighty percent of the oceans remain unexplored. The untapped biological resources present in oceans may be fundamental in solving several of the world's public health crises of the 21st century, which span from the rise of antibiotic resistance in bacteria, pathogenic fungi and parasites, to the rise of cancer incidence and viral infection outbreaks. In this review, health risks as well as how marine bacterial derived natural products may be tools to fight them will be discussed. Moreover, an overview will be made of the research pipeline of novel molecules, from identification of bioactive bacterial crude extracts to the isolation and chemical characterization of the molecules within the framework of the One Health approach. This review highlights information that has been published since 2014, showing the current relevance of marine bacteria for the discovery of novel natural products.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 30