Silica-Supported Copper for the Preparation of trans-4,5-Diamino-Cyclopent-2-Enones under Continuous Flow Conditions

• Type: Article in International Scientific Journal
• Date: 2021

Authors

Gomes, RFA (Author) Other; Cavaca, LAS (Author) Other; Goncalves, JM (Author) Other; Ramos, R (Author) Other; Peixoto, AF (Author) FCUP; Arias Serrano, BI (Author) Other; Afonso, CAM (Author) Other

Journal

The Journal is awaiting validation by the Administrative Services.

Title: ACS SUSTAINABLE CHEMISTRY & ENGINEERING

Vol. 9 No. 17

ISSN: 2168-0485

Indexing

ISI Web of Knowledge - 2 Citations

Scopus - 3 Citations

Other information

Authenticus ID: P-00V-ZV7

DOI: 10.1021/acssuschemeng.1c00884

Abstract (EN): The formation of cyclopentenones from biomass derivatives has been developed by reacting furfurals with secondary amines using Lewis acid catalysis under batch conditions. The challenge of scaling up these processes leads to the development of a continuous flow procedure for the preparation of trans-4,5-diamino-cyclopentenones using silica-supported copper catalysts. These catalysts exhibited high efficiency and recyclability for the preparation of a broad scope of cyclic enones.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6