Combination of Cell-Penetrating Peptides with Nanoparticles for Therapeutic Application: A Review

• Type: Another Publication in an International Scientific Journal
• Date: 2019

Authors

Silva, S (Author) Other; Almeida, AJ (Author) Other; Nuno Vale (Author) ICBAS

Journal

Title: Biomolecules

Vol. 9 No. 9

Final page: 22

ISSN: 2218-273X

Publisher: MDPI

Indexing

ISI Web of Knowledge - 96 Citations

Scopus - 101 Citations

Other information

Authenticus ID: P-00Q-40D

DOI: 10.3390/biom9010022

Abstract (EN): Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid residues capable of penetrating biological barriers and cellular membranes. Furthermore, CPP have become an alternative strategy to overcome some of the current drug limitations and combat resistant strains since CPPs are capable of delivering different therapeutic molecules against a wide range of diseases. In this review, we address the recent conjugation of CPPs with nanoparticles, which constitutes a new class of delivery vectors with high pharmaceutical potential in a variety of diseases.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 24