Kinetic modelling of decyl acetate synthesis by immobilized lipase-catalysed transesterification of vinyl acetate with decanol in supercritical carbon dioxide

• Type: Article in International Scientific Journal
• Date: 2009

Authors

Oliveira, MV (Author) Other; Rebocho, SF (Author) Other; Ribeiro, AS (Author) Other; Maria Eugénia Macedo (Author) FEUP; José Miguel Loureiro (Author) FEUP

Journal

Title: Journal of Supercritical Fluids

Vol. 50

Pages: 138-145

ISSN: 0896-8446

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 18 Citations

ISI Web of Science

Scopus - 19 Citations

Scientific classification

FOS: Engineering and technology > Other engineering and technologies

CORDIS: Technological sciences > Engineering > Chemical engineering

Other information

Authenticus ID: P-003-GA3

DOI: 10.1016/j.supflu.2009.05.003

Abstract (EN): The synthesis of decyl acetate, by the transesterification of vinyl acetate with decanol, was studied using supercritical CO(2) as solvent and immobilized Candida antarctica lipase B as catalyst (Novozym (R) 435). The enzymatic content was determined for each particle size of the catalyst, indicating that the enzyme is located in an external shell of the particle, following an "egg-shell" distribution, with an estimated thickness of ca. 60 mu m, independent of the particle size. The reaction was enhanced by increasing the enzyme loading, the concentration of vinyl acetate and the temperature: it was inhibited by excess of decanol and by increasing the pressure. A simplified model, based on the Ping-pong bi-bi mechanism with competitive inhibition by the alcohol, was proposed for the transesterification of vinyl acetate with decanol at 35 degrees C and 100 bar, and it was found to be suitable to represent the kinetic data.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8