To what extent is a constant volume design worse than a minimum volume design for a series of CSTR's?

• Type: Article in International Scientific Journal
• Date: 1995

Authors

F. Xavier Malcata (Author) Other

Journal

Title: Bioprocess Engineering

Vol. 13

Pages: 105-107

ISSN: 0178-515X

Publisher: Springer

Indexing

Scopus - 5 Citations

Other information

Authenticus ID: P-00F-GPV

DOI: 10.1007/s004490050142

Abstract (EN): The balance equations for substrate in a cascade of CSTR's undergoing an enzyme-catalyzed reaction following Michaelis-Menten kinetics are developed in dimensionless form. Analytical expressions relating the intermediate concentrations are independently obtained for the cases of minimum overall volume and constant volume. The fractional deviations between the overall volumes following these two design criteria are calculated and presented for several values of the relevant parameters. For situations of practical interest, the fractional deviation is below 10%. Increasing values of the Michaelis-Menten parameter. K(m) (or decreasing values of the number of reactors in the cascade, N) lead to lower values of the maximum deviation; this maximum deviation is attained at lower conversions of substrate when K(m) is increased or N decreased.

Language: English

Type (Professor's evaluation): Scientific