Tools for mapping high-throughput sequencing data

• Type: Another Publication in an International Scientific Journal
• Date: 2012

Authors

Nuno A Fonseca (Author) FCUP; Rung, J (Author) Other; Brazma, A (Author) Other; Marioni, JC (Author) Other

Journal

Title: Bioinformatics

Vol. 28

Pages: 3169-3177

ISSN: 1367-4803

Publisher: Oxford University Press

Indexing

ISI Web of Knowledge - 147 Citations

Other information

Authenticus ID: P-009-RQC

DOI: 10.1093/bioinformatics/bts605

Abstract (EN): Motivation: A ubiquitous and fundamental step in high-throughput sequencing analysis is the alignment (mapping) of the generated reads to a reference sequence. To accomplish this task numerous software tools have been proposed. Determining the mappers that are most suitable for a specific application is not trivial. Results: This survey focuses on classifying mappers through a wide number of characteristics. The goal is to allow practitioners to compare the mappers more easily and find those that are most suitable for their specific problem.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9