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Enantioseparation on amylose triso,5-dimethoxyphenyl carbamate): Application to commercial pharmaceutical chiral drugs

Title
Enantioseparation on amylose triso,5-dimethoxyphenyl carbamate): Application to commercial pharmaceutical chiral drugs
Type
Article in International Scientific Journal
Year
1999
Authors
Cass, QB
(Author)
Other
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Tiritan M.E.
(Author)
FFUP
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Calafatti, SA
(Author)
Other
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Matlin, SA
(Author)
Other
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Journal
Vol. 22
Pages: 3091-3099
ISSN: 1082-6076
Publisher: Taylor & Francis
Indexing
Other information
Authenticus ID: P-009-14R
Abstract (EN): The enantioselectivity of the amylose tris(3,5- dimethoxyphenyl carbamate) phase towards some ß-blockers was investigated. A sensitive HPLC method was developed for the enantiomers of metoprolol and betaxolol. The validated methods were suitable for the analysis of enantiomeric composition in a variety of pharmaceutical formulations of both drugs.
Language: English
Type (Professor's evaluation): Scientific
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