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Comparison between CDC and WHO BMI z-score and their relation with metabolic risk markers in Northern Portuguese obese adolescents

Title
Comparison between CDC and WHO BMI z-score and their relation with metabolic risk markers in Northern Portuguese obese adolescents
Type
Article in International Scientific Journal
Year
2015
Authors
Henrique Nascimento
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Cristina Catarino
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FFUP
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Denisa Mendonca
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FMUP
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Pedro Oliveira
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Ana Ines Alves
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Ana Filipa Medeiros
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Petronila Rocha Pereira
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Carla Rego
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Helena Ferreira Mansilha
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Luisa Aires
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J. Mota
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Alexandre Quintanilha
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Alice Santos Silva
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Luis Belo
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Journal
Vol. 7
Initial page: 32
ISSN: 1758-5996
Publisher: Springer Nature
Scientific classification
FOS: Medical and Health sciences > Clinical medicine
Other information
Authenticus ID: P-00G-493
Abstract (EN): Background: Growth-curves are an important tool for evaluating the anthropometric development in pediatrics. The different growth-curves available are based in different populations, what leads to different cut-offs. Pediatric obesity tracks into adulthood and is associated with increased cardiovascular risk. The accurate assessment of a child nutritional status using growth-curves can indicate individuals that are either obese or in risk of becoming obese, allowing an early intervention. Moreover, the association between the data obtained from growth-curves with specific metabolic risk factors further highlights the importance of these charts. This study aimed to evaluate the associations between body mass index z-score (BMIzsc), determined using the growth-curves from the Centre for Disease Control and Prevention (CDC) and from the World Health Organization (WHO), with cardiovascular risk factors, represented here by metabolic syndrome (MS) and insulin resistance (IR) related parameters. The study involved 246 obese adolescents (10-18 years, 122 females). MS was defined according to the International Diabetes Federation. IR was considered for HOMA-IR greater than 2.5. Findings: No difference between both BMIzsc in identifying MS was noticeable by a ROC analysis. For both indexes the area-under-the-curve increased for older groups, particularly for males. CDC-BMIzsc was the best predictor of MS by logistic regression when all population was considered, however MS was better predicted by WHO-BMIzsc for females and by CDC-BMIzsc for males. Younger girls and older boys were in increased risk for MS. Similar results were obtained for IR. Conclusions: A significant difference between the two BMIzsc regarding their association with MS and IR was not clear, being these associations weaker in younger individuals.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 5
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