Integrated Project in Biological Engineering I

Code:

EBE0131

Acronym:

PIEB1

Keywords
Classification	Keyword
OFICIAL	Biological Engineering

Instance: 2010/2011 - 2S

Active?	Yes
Responsible unit:	Department of Chemical and Biological Engineering
Course/CS Responsible:	Master in Bioengineering

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIB	13	Syllabus	3	-	7	70	189

Teaching language

Suitable for English-speaking students

Objectives

This course unit aims to familiarise students with the laboratory demonstration of some biotechnological processes, which are approached in other theoretical course units. Students will be asked to carry out practical assignments, and they should base their projects with knowledge acquired in the course units of Bioreaction Engineering I and II.
Since this course unit is manly laboratory-oriented, the assessment will be essentially based on reports. Students’ performance during classes will also be taken into account.
Students will be asked to carry out six practical assignments (teamwork). Besides, they have to write reports (five group reports and one individual report).

Program

1. Assessment of the growth of simple and mixed microbial populations (Pseudomonas fluorescens e Saccharomyces cerevisiae) and characterization of kinetic parameters.
2. Study of aeration and agitation in tanks – KL.a value to several conditions by dynamic and chemical methods.
3. Determination of invertase kinetic constants in free cells and immobilized in alginate.
4. Demonstration of the growth of Saccharomyces cerevisiae in chemostat- study of the effect of dilution rate
5. Obtaining G-penicillin by fed-batch operation and determination of its concentration using a biosensor.
6. Open project (mathematical simulation of a biological process).
7. Proposal and assessment of alternatives of the assignments

Mandatory literature

James M. Lee; Biochemical engineering. ISBN: 0-13-085317-8
Andreas S. Bommarius, Bettina R. Riebel; Biocatalysis. ISBN: 978-3-527-30344-1

Complementary Bibliography

James E. Bailey, David F. Ollis; Biochemical engineering fundamentals. ISBN: 0-07-066601-6
Cabral J.M.S., Aires-Barros M.R., Gama M.; Engenharia Enzimática. , Lidel – edições técnicas, Lda., 2003
Fonseca M.M., Teixeira J.A.; Reactores biológicos – fundamentos e aplicações. , Lidel – edições técnicas, Lda., 2007

Teaching methods and learning activities

Classes will be based on the formal presentation of some theoretical concepts and experimental methodologies.
Students will be asked to carry out laboratory assignments: characterization of the mode of operation of bioreactors with examples of processes of production and purification of bio-products.

Software

Acrobat Professional 9.0 Win AOO License IE

keywords

Natural sciences > Biological sciences > Biological engineering

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
Attendance (estimated)	Participação presencial	0,00
	Total:	-	0,00

Calculation formula of final grade

Final Grade will be based on the following assessment components:
Reports of the experimental assignments – 45% of the final grade
Individual report of one experimental assignment – 25% of the final grade
Presentation of the report of one experimental assignment – 5% of the final grade
Continuous Assessment- students’ performance during classes- 25% of the final grade

To complete the course unit, students have to reach a minimum grade of 9.5. Besides, they cannot miss more classes than allowed by the rules.

Special assessment (TE, DA, ...)

Students with a special status have to do the assignments and deliver them on the same date as regular students. All students will be assessed in the same way.

Classification improvement

Students can improve their grades by attending a laboratory exam which will be based on an assignment to be defined by the professor. Also, students have to write a report and give a presentation about the assignment