Quercitrin: an antileishmanial flavonoid glycoside from Kalanchoe pinnata.

• Type: Article in International Scientific Journal
• Date: 2006

Authors

Michelle F. Muzitano (Author) Other; Elaine A. Cruz (Author) Other; Ana Paula de Almeida (Author) FFUP; Silvia A. G. Da Silva (Author) Other; Carlos R. Kaiser (Author) Other; Catherine Guette (Author) Other; Bartira Rossi-Bergmann (Author) Other; Sônia S. Costa (Author) Other

Journal

Title: Planta Medica

Vol. 72 No. 1

Pages: 81-83

ISSN: 0032-0943

Publisher: Thieme

Indexing

ISI Web of Science

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

CORDIS: Health sciences

Other information

Resumo (PT): Quercitrin (quercetin 3-O-α-L-rhamnopyranoside), one of the constituents of the biologically active aqueous extract obtained from Kalanchoe pinnata, is demonstrated to be a potent antileishmanial compound (IC50 ≈ 1 μg/mL) with a low toxicity profile. This is the first time that antileishmanial activity is demonstrated for a flavonoid glycoside. <br> <br>

Abstract (EN): Quercitrin (quercetin 3-O-α-L-rhamnopyranoside), one of the constituents of the biologically active aqueous extract obtained from Kalanchoe pinnata, is demonstrated to be a potent antileishmanial compound (IC50 ≈ 1 μg/mL) with a low toxicity profile. This is the first time that antileishmanial activity is demonstrated for a flavonoid glycoside. <br> <br>

Language: English

Type (Professor's evaluation): Scientific