PHENOBARBITURATE FLOW-THROUGH ELECTRODE FOR FLOW-INJECTION ANALYSIS OF PHARMACEUTICAL PRODUCTS

• Type: Article in International Scientific Journal
• Date: 1992

Authors

LIMA, JLFC (Author) FFUP; MONTENEGRO, MCBSM (Author) FFUP; ALONSOCHAMARRO, J (Author) Other; BARTROLI, J (Author) Other; GARCIARAURICH, J (Author) Other

Journal

Title: Analytical Sciences

Vol. 8

Pages: 19-23

ISSN: 0910-6340

Publisher: Japan Society for Analytical Chemistry

Indexing

ISI Web of Knowledge - 12 Citations

Scopus - 10 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-001-PVD

DOI: 10.2116/analsci.8.19

Abstract (EN): We constructed, tested and applied a tubular 5-ethyl-5-phenylbarbiturate ion-selective electrode based on tetraoctylammonium 5-ethyl-5-phenylbarbiturate dissolved in o-nitrophenyl octyl ether and immobilized on poly(vinyl chloride). The intrinsic features of the proposed electrode were assessed by using a low-dispersion single-channel flow injection analysis (FIA) system for performing repeated calibrations with sodium 5-ethyl-5-phenylbarbiturate standards, whose ionic strength was adjusted to 0.1 M with 0.033 M sodium sulfate. The determination of 5-ethyl-5-phenylbarbiturate in pharmaceutical preparations was accomplished by intercalating the proposed electrode into a two-channel FIA manifold. The results obtained were compared with those provided by the British Pharmacopoeia standard method.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5