Weight variation before and after surgery in Parkinson's disease: A noradrenergic modulation?

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2012

Autores

Joana Guimaraes (Autor) FMUP; Eduardo Moura (Autor) Outra; Maria Augusta Vieira Coelho (Autor) FMUP; Carolina Garrett (Autor) FMUP

Revista

Título: Movement Disorders

Vol. 27

Páginas: 1078-1082

ISSN: 0885-3185

Editora: Wiley-Blackwell

Indexação

ISI Web of Knowledge - 21 Citações

Scopus - 21 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina clínica

CORDIS: Ciências da Saúde

Outras Informações

ID Authenticus: P-002-799

DOI: 10.1002/mds.25063

Abstract (EN): Changes in the nutritional profile of patients with Parkinson's disease have been reported before and after deep brain stimulation surgery. The major determinants of the weight variation in Parkinson's disease are not yet understood, and the mechanism seems complex. Based on the influence of the sympathetic nervous system in metabolic syndrome obesity, the intent of the present review is to consider the role of noradrenergic modulation on weight variations in Parkinson's disease. In this review the authors raise the following hypothesis: weight variation in Parkinson's disease before and after deep brain stimulation of the subthalamic nucleus could be influenced by noradrenergic interaction between the locus coeruleus, subthalamic nucleus, and hypothalamic nucleus. (c) 2012 Movement Disorder Society

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5