Weight variation before and after surgery in Parkinson's disease: A noradrenergic modulation?

• Type: Another Publication in an International Scientific Journal
• Date: 2012

Authors

Joana Guimaraes (Author) FMUP; Eduardo Moura (Author) Other; Maria Augusta Vieira Coelho (Author) FMUP; Carolina Garrett (Author) FMUP

Journal

Title: Movement Disorders

Vol. 27

Pages: 1078-1082

ISSN: 0885-3185

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 21 Citations

Scopus - 21 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

CORDIS: Health sciences

Other information

Authenticus ID: P-002-799

DOI: 10.1002/mds.25063

Abstract (EN): Changes in the nutritional profile of patients with Parkinson's disease have been reported before and after deep brain stimulation surgery. The major determinants of the weight variation in Parkinson's disease are not yet understood, and the mechanism seems complex. Based on the influence of the sympathetic nervous system in metabolic syndrome obesity, the intent of the present review is to consider the role of noradrenergic modulation on weight variations in Parkinson's disease. In this review the authors raise the following hypothesis: weight variation in Parkinson's disease before and after deep brain stimulation of the subthalamic nucleus could be influenced by noradrenergic interaction between the locus coeruleus, subthalamic nucleus, and hypothalamic nucleus. (c) 2012 Movement Disorder Society

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5