Sequential reactions from catalytic hydroformylation toward the synthesis of amino compounds

• Tipo: Artigo em Revista Científica Internacional
• Data: 2017

Autores

Almeida, AR (Autor) Outra; Carrilho, RMB (Autor) Outra; Peixoto, AF (Autor) FCUP; Abreu, AR (Autor) Outra; Silva, A (Autor) Outra; Pereira, MM (Autor) Outra

Revista

Título: Tetrahedron

Vol. 73

Páginas: 2389-2395

ISSN: 0040-4020

Editora: Elsevier

Indexação

ISI Web of Knowledge - 7 Citações

Outras Informações

ID Authenticus: P-00M-QNS

DOI: 10.1016/j.tet.2017.03.023

Abstract (EN): Different families of new amino compounds were efficiently synthesized, through optimized sequential processes, involving rhodium catalyzed hydroformylation as the key step. The selection of appropriate hydroformylation catalytic systems and reaction conditions allowed obtaining aldehydes derived from several n-alkyl olefins, cholest-4-ene and 3-vinyl-1H-indole, which were subsequently transformed, in one-pot, in to alpha-amino acids via hydroformylation/Strecker reaction, and in to tertiary amines via hydroaminomethylation, with excellent yields.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7