Role of TiO2-based photocatalysts on the synthesis of the pharmaceutical precursor benzhydrol by UVA-LED radiation

• Tipo: Artigo em Revista Científica Internacional
• Data: 2020

Autores

Lopes, JC (Autor) Outra; Sampaio, M.J. (Autor) FEUP; Rosa, B (Autor) Outra; Lima, MJ (Autor) Outra; Joaquim Luís Faria (Autor) FEUP; Claudia G Silva (Autor) FEUP

Revista

Título: Journal of Photochemistry and Photobiology A: Chemistry

Vol. 391

ISSN: 1010-6030

Editora: Elsevier

Indexação

ISI Web of Knowledge - 0 Citações

ISI Web of Science

Scopus - 1 Citação

Projetos Associados

LED-NETmix - LED-NETmix: um fotoreator inovador para a intensificação de processos em síntese química

MicroPhotOGen - Dispositivos foto-eletroquímicos microfluídicos para oxigenação do sangue

IF/00514/2014/CP1249/CT0004 - Desafiando a síntese em química fina: uma nova abordagem utilizando fotocatalisadores isentos de metais

Outras Informações

ID Authenticus: P-00R-K20

DOI: 10.1016/j.jphotochem.2019.112350

Abstract (EN): The influence of several reactional parameters was investigated on the photocatalytic reduction of benzophenone to the pharmaceutical precursor benzhydrol under UVA-LED radiation. The optical semiconductor titanium dioxide was loaded with 1.0 wt% of noble metals (Pd, Pt and Au) by incipient wetness impregnation method. The TiO2-based materials were characterized by various techniques. Results showed that the benzhydrol selectivity is highly influenced by the nature of the solvent and the presence of KOH (acting as nucleophilic agent). The most efficient system was obtained using 2-propanol, 5.0 mM of KOH and 0.1 g L-1 of catalyst, achieving 100 % selectivity of benzhydrol after 10 mM reaction. Among the TiO2-based materials, the Pd/TiO2 showed high efficiency for benzhydrol formation (in absence KOH) with an enhancing of c.a. 49 % compared with neat TiO2. The decrease of photoluminescence intensity observed for Pd/TiO2 material suggests an effective electron transfer from TiO2 to Pd nanoparticles.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9