Magnetoliposomes based on nickel/silica core/shell nanoparticles: Synthesis and characterization

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

Rodrigues, ARO (Autor) Outra; Gomes, IT (Autor) Outra; Almeida, BG (Autor) Outra; araujo, j. p. (Autor) FCUP; Castanheira, EMS (Autor) Outra; Coutinho, PJG (Autor) Outra

Revista

Título: Materials Chemistry and Physics

Vol. 148

Páginas: 978-987

ISSN: 0254-0584

Editora: Elsevier

Indexação

ISI Web of Knowledge - 8 Citações

Scopus - 10 Citações

Outras Informações

ID Authenticus: P-009-YCN

DOI: 10.1016/j.matchemphys.2014.09.008

Abstract (EN): In the present work, nickel magnetic nanoparticles with diameters lower than 100 nm, with and without silica shell, were synthesized by microheterogeneous templating. The magnetic properties of the nanoparticles show a typical ferromagnetic behavior with a coercive field of 80 Oe. Dry magnetoliposomes (DMLs) with diameter between 58 nm and 76 nm were obtained from the synthesis of nanoparticles in the presence of a lipid or surfactant layer, and aqueous magnetoliposomes (AMLs) were obtained by encapsulation of the nanoparticles in liposomes. FRET (Forster resonance energy transfer) experiments were performed to study the non-specific interactions between aqueous magnetoliposomes and giant unilamellar vesicles (GUVs), as models of cell membranes. It was possible to detect membrane fusion between GUVs and AMLs containing both NBD-C-6-HPC (donor) and the dye Nile Red (acceptor).

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 10