Official Code: | 9015 |
Acronym: | L:BQ |
Description: | A Licenciatura em Bioquímica tem como objetivo a compreensão dos processos biológicos a diferentes níveis de complexidade (moléculas, células, tecidos, órgãos e organismos), sendo eminentemente interdisciplinar. A parceria entre a FCUP e o ICBAS constitui uma mais-valia, permitindo que seja lecionada nas duas instituições e promovendo o contacto com realidades científicas complementares. Este ciclo de estudos promove a formação de profissionais com competências científicas e tecnológicas que permitem: a aquisição de conhecimentos sólidos na área da Bioquímica, e também na Biofísica, na Biologia Molecular e Celular, na Fisiologia e na Microbiologia e ainda na Imunologia, na Química Alimentar ou na Ecologia; o desenvolvimento de atividade profissional em laboratórios de investigação, departamentos de l&D em empresas relacionadas com biotecnologia e em laboratórios de análises químicas e biológicas; a continuação para uma formação avançada. |
The Cell is the fundamental unit of life and its structure and functions are central to Biology. The Curricular Unit (UC) Cell Biology (BC) aims to provide the knowledge necessary to understand the architecture of the cell and the integrated functioning of cellular life. It is also the objective of this UC to work its contents in an application context, and to provide hands-on contact with different types of cells, organelles and cellular processes, as well as with some of the fundamental techniques and methodologies for the construction of the knowledge in Cell Biology (eg, optical microscopy, electron microscopy, cellular fractionation).
The aim of this course is that the student:
- masters some basic techniques of differential and integral calculus of one variable (calculation of derivatives, primitives and integrals, solution of differential equations) and recognizes some of its applications;
- Master some basic concepts of Probability and Statistics, necessary for the development of this subject in the respetive Curricular Unit (UC) of the second year.
The course "Química I (1st year, 1st semester) is the first chemistry course in the Chemistry and Biochemistry B.Sc's. The main objective is to provide a solid understanding of the essential chemistry concepts necessary for further applications in other more specialized courses and multidisciplinary courses.
The program covers the general principles about atoms and molecules, constituents of matter, their transformations, either by chemical reaction or by phase transition, and also the thermodynamic principles that govern these transformations of matter and energy associated with them.
Search scientific information on the Internet in a systematic way. Handle and present numerical data in a clear and rigorous way.
The Chemistry Lab (Q1013) course comprises a set of practical works, involving several experimental techniques and procedures with the aim of providing the students with a basic training in chemistry laboratory techniques.
The course "Química II" is for the Chemistry and Biochemistry B.Sc's. The main objective is to provide a solid understanding of the essential chemistry concepts necessary for further applications in other more specialized courses and multidisciplinary courses.
The main topics covered are Chemical Kinetics, Chemical Equilibrium, Acid-Base, Entropy, Gibbs energy, Electrochemistry, Metals and Transition Metal Chemistry.
Aims:
- Provide knowledge of the main functional classes of organic molecules, focusing on their nomenclature, three-dimensional structure, reactivity, synthesis methods and mechanisms of the main reactions in which they are involved.
Introduction to the fundamental concepts, principles and methods of statistics. Particular attention is given to the understanding of concepts and the critical use of methods,while maintaining mathematical treatment at an elementary level.
Introduction to R software and its basic application in statistics.
In theoretical classes, students are expected to acquire basic knowledge of Analytical Chemistry, trying to highlight the importance of analysis in solving real problems. In the theoretical-practical classes are carried out exercises on the subject versed in the theoretical classes. In the practical classes 4 or 5 lab work are carried out.
Topics of Physical Chemistry and their applications to biological systems.
The students should acquire the notions of basic physical chemistry concepts, as well as understand their application to biology.
Introduction to colloidal systems.
To know the different families of organic molecules in terms of their reactivity, the reaction mechanisms in which they are involved and their synthesis. To understand the relationship between structure and function of organic molecules. Demonstrate, through examples from everyday life, the role of organic chemistry in the development of some areas of modern biology, medicine and the synthesis of new products and materials. Apply the chemical concepts learnt to concrete situations in life sciences and industry.
Practical application of concepts taught in the discipline Biological Physical Chemistry (previous semester). Application of various physical methods to the study of different reactions. Learning/training in data processing, with recourse to Excel or similar programs. Learning/improving skills in presentation of scientific results and its discussion.
Understand the role of metal ions in biological systems at a molecular level and the basic chemical principles that promote their reactivity. During classes exemples will be given of the importance of bioinorganic chemistry in several fields (pharmacology, medicine, agriculture, metallurgy, veterinary, among others) .
The student must be able to use and understand the need of additives. General knowlgement in the production and control of the major product lines in food industry: bakery products, beverages, dairy products, fats and oils, meat, fish and poultry.
The main goal is to provide scientific training in Environmental Chemistry:
application of chemical principles to the understanding of environmental phenomena, including the role of living organisms; understanding the processes that take place in the various environmental compartments and how human activity interacts with natural processes; application of chemical principles to the great challenge of humanity - the recovery, maintenance and improvement of environmental quality.
Other goals: improve the abilities to interpret texts, find information, synthesize and transmit knowledge in the field of Environmental Chemistry and acquire a global perspective of Environmental Chemistry.
The student must develop a broad knowledge of the entire drug discovery and development pipeline, from identifying the target to the market entry, including economic and legal aspects and registration of patents.
Given a biological target, the student should also be able to identify a lead compound. To predict its binding pose and optimize computationally the energy of interaction between the two species when the target structure is known. Estimate the energetic contribution of the solvent in the receptor-ligand equilibrium and the role of hydrophobicity and flexibility. The student must know the requirements of a drug to have good absorption, distribution, metabolism, and excretion properties. In short, the student must have the capacity, on an autonomous basis, to make consistent and relevant proposals of ligands with good affinity for the target, with favorable pharmacokinetic properties, and with viability for commercial development.