Evaluation of cinnamaldehyde and cinnamic acid derivatives in microbial growth control

• Type: Article in International Scientific Journal
• Date: 2019

Authors

J. F. Malheiro (Author) Other; J.-Y. Maillard (Author) Other; F. Borges (Author) Other; Manuel Simões (Author) FEUP

Journal

The Journal is awaiting validation by the Administrative Services.

Title: INTERNATIONAL BIODETERIORATION & BIODEGRADATION

Vol. 141

Pages: 71-78

ISSN: 0964-8305

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 9 Citations

ISI Web of Science

Scopus

Associated Projects

LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

Other information

Authenticus ID: P-00Q-Q12

DOI: 10.1016/j.ibiod.2018.06.003

Abstract (EN): The conspicuous absence of novel and effective strategies to control microbial growth, both in the food and healthcare industries and evidence of increasing microbial resistance to conventional biocides has led to a search for novel antimicrobials and growth prevention strategies. In this study, 15 phytochemicals and derivatives, structurally-related to cinnamic acid and cinnamaldehyde, were assessed for their effects on the growth of Escherichia colt, Staphylococcus aureus and Enterococcus hirae. Their effects were compared to seven commonly used biocides (hydrogen peroxide, sodium hypochlorite, chlorhexidine, cetyltrimethylammonium bromide, triclosan, o-phthalaldehyde and lactic acid). All phytochemicals and derivatives increased lag phase and culture doubling time of the tested bacteria. Cinnamic acid and other derivatives inhibited bacterial growth. The MIC of cinnamaldehyde was comparable to o-phthalaldehyde and sodium hypochlorite and lower than hydrogen peroxide and lactic acid. The effect of methyl trans-cinnamate on bacterial growth was more evident against Gram-negative bacteria. It also inhibited quorum sensing in Chromobacterium violaceum. The effect of phytochemicals against sessile bacteria was low: < 1 log CFU.cm(-2). Inhibition of quorum sensing and of bacterial growth supports the fact that phytochemicals are an interesting source of antimicrobials with potential use as biocides or more likely as additives to improve the efficacy of current biocidal formulations and preservative systems.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8