Abstract (EN):
The heart is a target organ for the toxicity of several drugs. These drugs exert cardiotoxicity, in general, through four mechanisms: membrane ionic flux alterations, oxidative stress, 'Ca2+ overload' and mitochondrial inactivation. The present review will focus on different cardiotoxic drugs especially on those, which express their toxicity by oxidative stress.
Language:
Portuguese
Type (Professor's evaluation):
Scientific