Code: | MV127 | Acronym: | QBII |
Keywords | |
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Classification | Keyword |
OFICIAL | Basic Sciences |
Active? | Yes |
Responsible unit: | Chemistry |
Course/CS Responsible: | Integrated Masters Degree in Veterinary Medicine |
Acronym | No. of Students | Study Plan | Curricular Years | Credits UCN | Credits ECTS | Contact hours | Total Time |
---|---|---|---|---|---|---|---|
MIMV | 100 | Official Study Plan | 1 | - | 5 | 70 | 135 |
Teacher | Responsibility |
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Maria Adelina Coelho Ribeiro Costa |
Theoretical classes: | 3,00 |
Laboratory Practice: | 2,00 |
Type | Teacher | Classes | Hour |
---|---|---|---|
Theoretical classes | Totals | 1 | 3,00 |
Maria da Conceição Santos Silva Rangel Gonçalves | 0,214 | ||
Maria Adelina Coelho Ribeiro Costa | 2,786 | ||
Laboratory Practice | Totals | 4 | 8,00 |
Maria Adelina Coelho Ribeiro Costa | 2,00 |
1. To rationalize living systems in terms of basic Chemistry principles. To present Biological Chemistry as a mere subset of Chemistry.
2. To correlate knowledge from Organic and Inorganic Chemistry with Biological Chemistry.
3. To aquire specific knowledge about biological molecules and and cellular chemistry organization.
1. Knowledge of the biologically important carbon compounds reactions and their mechanisms. Basic organic chemistry problem solving.
2. Structural knowledge of the most important types of biological molecules.
3. Understanding of the importance of molecular recognition, intermolecular interaction and the hydrophobic effect in biological chemistry.
4. Ability to explain the function and action mechanism of biological compounds based on its molecular structure and reactivity, namely enzymes' catalysis, kinetics and regulation.
5. Understanding of the main metabolism global organization, namely the integration of anabolism and catabolism made by NAD (and FAD) and ATP (and other NTPs).
Theoretical
1. Nucleophilic substitution and elimination reactions. SN1 and SN2 reactions. Reactive Intermediates in Organic Chehemistry: free radicals, carbocations, carbanions. Electrophiles and Nucleophiles. Homolysis and heterolysis of covalent bonds. SN1 and SN2 reactions. E1 and E2 reactions.
2. Benzenoid aromatic compounds. Polycyclic Aromatic Hydrocarbons and heterocyclic aromatic compounds.
3. Alcohols and phenols: Physical and chemical properties of alcohols and phenols.
4. Aldehydes and ketones. The carbobyl group. Nucleophilic addition and condensation.
5. Carbohydrates-monosacharides. Glycosidic linkage. Oligosacharides and polysacharides.
6. Carboxylic acids and derivatives - Acidity. Nucleophilic substitution.
7. Lipids - The hydrophobic effect. Fatty acids, acylglycerides, phosphoglycerides and sphingolipids. Terpenoids, steroids and icosanoids.
8. Amines - Basicity. Characteristic reactions. Alkaloids and biogenic amines.
9. Proteins - Aminoacids. Peptidic bond. Structure and conformation. Biological functions.
10. Nucleic acids - Nucleotides. DNA and RNA.
11. Basic aspects of primary metabolism organization and energetics.
12. Enzymes - Molecular rcognition. Mechanisms, kinetics and regulation of enzymatic catalysis. Coenzymes and cofactors.
Laboratorial
1. Identification of carbohydrates.
2. Solutions preparation.
3. Spectrophotometric measure of human serum total colesterol.
4. Denaturation and spectrophotometry of DNA.
5. Invertase kinetics
Theoretical classes, using Powerpoint presentations. Theoretical-practical classes of problem solving and matters related with laboratorial works. Laboratorial classes where the students work in groups of up to 3, following a written protocol.
Designation | Weight (%) |
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Exame | 70,00 |
Teste | 20,00 |
Trabalho laboratorial | 10,00 |
Total: | 100,00 |
Designation | Time (hours) |
---|---|
Estudo autónomo | 65,00 |
Frequência das aulas | 70,00 |
Total: | 135,00 |
Each student will have to:
At the end of the course unit, these assignments will be assessed and the final average obtained will correspond to the Distributed evaluation classification (DEC). This classification will be published before the Examination and will be part of the Final Grade.
Option 1: Examination divided into A1 (20 values, Intermediate Assessment 1) and A2 (20 values, Normal Exam Period):
EN = 1/2 A1 + 1/2 A2
Option 2: Final Exam (includes all subjects taught)
EN = 20 points
The final grade (F) will be the sum of the Final Examination Grade (EN) and the Distributed evaluation classification (DEC), according to the formula:
F = 0.7 EN + DEC
EN ≥ 9,5 for final approval
EN ≥ 9,5 for final approval