Thermodynamics

Code:

EBE0006

Acronym:

TERM

Keywords
Classification	Keyword
OFICIAL	Basic Sciences

Instance: 2020/2021 - 2S

Active?	Yes
Responsible unit:	Chemistry
Course/CS Responsible:	Master in Bioengineering

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIB	109	Syllabus	1	-	6	56	162

Teaching language

Portuguese

Objectives

The student is expected to understand and be able to handle a tool that allows not only to understand the mechanisms by which the energy flows in a living cell but also the thermodynamic analysis of industrial processes.

The student must be able to visualize photosynthesis, metabolism and cellular respiration processes in an integrated way and realize that life depends on a carbon-oxygen cycle that is finely regulated by other elements and initiated in most organisms by solar energy.

The student will also be able to calculate the thermodynamic properties of fluids, perform phase-equilibria calculations, and analyse industrial processes including power cycles and refrigeration.

Learning outcomes and competences

The student must be able to visualize photosynthesis, metabolism and cellular respiration processes in an integrated way and realize that life depends on a carbon-oxygen cycle that is finely regulated by other elements and initiated in most organisms by solar energy.

The student will also be able to calculate the thermodynamic properties of fluids, perform phase-equilibria calculations, and analyse industrial processes including power cycles and refrigeration.

Working method

Presencial

Program

TP classes

1. Bioenergetics
Physical and chemical principles, mathematical and biological approaches. Energy and LifeSources and transformation of energy. The Chemical Elements of Life.

2. Fundamentals of atomic structure.

3. Chemical bonding

4. First Principle of Thermodynamics
Internal energy and Enthalpy
Bond enthalpies

5. Second and Third Principle sof Thermodynamics
Entropy and Gibbs function
The chemical potential

6. Phase equilibria in biology

7. Chemical equilibria in biology

8. Biological transport

8. Energetics of Cellular Respiration and of Photosynthesis

10. Thermodynamic properties of fluids

11. Phase Equilibrium (VLE, LLE, SLE and SVE)

12. Thermodynamic analysis of processes

 

Laboratory classes

1. Calorimetry: ΔH⁰ for acid-base, dissolution and formation reactions

2. Potentiometry: K_eq, ΔG⁰, ΔH⁰ and ΔS⁰ of glycine desprotonations

3. UV spectrophotometry: K_eq, ΔG⁰, ΔH⁰ and ΔS⁰ of DNA denaturation

4. VIS spectrophotometry: kinetics and thermodynamics of invertase-catalysed hydrolysis, ΔG^‡, ΔH^‡ e ΔS^‡ activation parameters

Mandatory literature

Atkins Peter; Physical chemistry for the life sciences. ISBN: 9780199280957
Lehninger Albert L.; Principles of biochemistry
J. M. Smith; Introduction to chemical engineering thermodynamics. ISBN: 007-124708-4

Teaching methods and learning activities

The main objective is the acquisition of theoretical and technical competencies to use thermodynamics as a tool to understand energy flow in a cell. The thermodynamic analysis of industrial processes is also important.

The theoretical concepts are new and need to be learned/ developed, and the laboratory component is fundamental for data acquisition and data analysis.

The theoretical content of the curricular units in biophysics and thermodynamics (both in the 2nd semester of the 1st year) has been developed considering a rational integrated approach.

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Designation	Weight (%)
Teste	100,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Estudo autónomo	106,00
Frequência das aulas	42,00
Trabalho laboratorial	14,00
Total:	162,00

Eligibility for exams

Are exempted from verification of attendance all cases laid down by law.

Calculation formula of final grade

Final grade = ((0.70 * Grade Test 1 + 0.3 *Grade Test 2)*0.75 + 0.25 * Grade Test 3)

Examinations or Special Assignments

Not applicable.

Internship work/project

Not applicable.

Special assessment (TE, DA, ...)

According to UP laws.

Classification improvement

According to UP laws.