Thermodynamics

Code:

EBE0006

Acronym:

TERM

Keywords
Classification	Keyword
OFICIAL	Basic Sciences

Instance: 2017/2018 - 2S

Active?	Yes
Responsible unit:	Chemistry
Course/CS Responsible:	Master in Bioengineering

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIB	86	Syllabus	1	-	6	56	162

Teaching language

Suitable for English-speaking students

Objectives

The student is expected to understand and be able to handle a tool that allows not only to understand the mechanisms by which the energy flows in a living cell but also the thermodynamic analysis of industrial processes.

The student must be able to visualize photosynthesis, metabolism and cellular respiration processes in an integrated way and realize that life depends on a carbon-oxygen cycle that is finely regulated by other elements and initiated in most organisms by solar energy.

The student will also be able to calculate the thermodynamic properties of fluids, performing material and energy balances for different types of systems, and analyse industrial processes including power cycles and refrigeration.

Learning outcomes and competences

The student must be able to visualize photosynthesis, metabolism and cellular respiration processes in an integrated way and realize that life depends on a carbon-oxygen cycle that is finely regulated by other elements and initiated in most organisms by solar energy.

Working method

Presencial

Program

TP classes

1. Bioenergetics
Physical and chemical principles, mathematical and biological approaches.

2. Energy and Life
Sources and transformation of energy
The Chemical Elements of Life

3. First Principle of Thermodynamics
Internal energy and Enthalpy
Bond enthalpies

4. Second and Third Principle sof Thermodynamics
Entropy and Gibbs function
The chemical potential

5. Phase equilibria in biology

6. Chemical equilibria in biology

7. Biological transport

8. Energetics of Cellular Respiration

9. Energetics of Photosynthesis

10. Thermodynamic properties of fluids

11. Phase Equilibria (ELV, ELL, ESL e ESV)

12. Thermodynamic analysis of chemical processes

 

Laboratory classes

Calorimetric measurement of the enthalpy of acid-base and dissolution reactions

Potentiometric titration of glycine

Spectrophotometric study of DNA denaturation

Kinetics and thermodynamics study of enzyme invertase

Mandatory literature

Atkins Peter; Physical chemistry for the life sciences. ISBN: 9780199280957
Lehninger Albert L.; Principles of biochemistry

Teaching methods and learning activities

The main objective is the acquisition of theoretical and technical competencies to use thermodynamics as a tool to understand energy flow in a cell. The thermodynamic analysis of industrial processes is also important.

The theoretical concepts are new and need to be learned/ developed, and the laboratory component is fundamental for data acquisition and data analysis.

The theoretical content of the curricular units in biophysics and thermodynamics (both in the 2nd semester of the 1st year) has been developed considering a rational integrated approach.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	75,00
Trabalho laboratorial	25,00
Total:	100,00

Calculation formula of final grade

Final grade = (0.75 x theoretical grade)+(0.25 xlaboratory grade)