Code: | MV312 | Acronym: | FTI |
Keywords | |
---|---|
Classification | Keyword |
OFICIAL | Basic Sciences |
Active? | Yes |
Responsible unit: | Imuno-Physiology and Pharmacology |
Course/CS Responsible: | Integrated Masters Degree in Veterinary Medicine |
Acronym | No. of Students | Study Plan | Curricular Years | Credits UCN | Credits ECTS | Contact hours | Total Time |
---|---|---|---|---|---|---|---|
MIMV | 79 | Plan 2007 to 2017 | 3 | - | 4 | 64 | 108 |
To provide students with knowledge in General Pharmacology, with special reference to drug mechanisms of action (from molecules to the system), pharmacokinetics, relation of mechanisms of action to clinical response, side effects, clinical problems and toxicity and its use in Veterinary Therapeutics.
PRACTICAL LAB CLASSES
- Application of the scientific methodology and follow-up of different experimental protocols.
- Capability of solving practical problems. Organised team work.
- Basics of laboratory safety and good laboratory practices.
- Rules of handling, management and care of lab animals.
- Training in basic experimental techniques (e.g. weighing, preparing solutions etc.).
- Specific training in pharmacological experiments (e.g. preparing equipment, isolation of the preparations and registration of biological signals, evaluation of the effects promoted by the drugs applied etc).
- Drugs administration in required doses and concentrations for in vivo and in vitro experiments.
- Understanding basic pharmacology concepts such as performing dose-response curves, drugs action selection, routes of drugs in a living organism etc.
- Observation capability, quantification, experimental variability appraisal, evaluation and interpretation of experimental data.
THEORETICAL-PRACTICAL CLASSES:
- Teamwork capability.
- Time management, self-discipline and work capability without direct supervision.
- Autonomous problem solving. Information retrieve and bibliographical research.
- Handling of experimental results and conclusion obtained from different sources.
- Critical assessment of different sources.
- Presentation of a written piece of work (monograph).
- Competence with Microsoft office programs such as Word, Excel, Access, PowerPoint and others.
- The methodology for obtaining information and bibliographical research must include the use of databases and Internet (certification of the site’s quality).
- Mastery of communication skills (interpersonal and public speaking competencies).
- Evaluation of auto-didactism and development of interest in lifelong learning.
Students should have approved Anatomy, Physiology, Chemistry, Biochemistry, Microbiology, Immunology and Pathology.
THEORETICAL CLASSES PROGRAM
General Pharmacology – Introduction to pharmacology; Pharmacokinetics; Pharmacodynamics (Drug/receptor interactions, Transducing Systems); Regulatory systems (neurotransmitters, neuromodulators, autacoids, hormones); Peripheral autonomic nervous system (cholinergic and adrenergic divisions); Central nervous system pharmacology (stimulants, depressants, sedatives and hypnotics, anticonvulsants, antiparkinsonics, muscle relaxants); General and local anesthetics; Opioids; Non-steroidal anti-inflammatory drugs; drugs used in gout. Cholinergic transmission: cholinoceptor-activating and cholinesterase-inhibiting drugs; cholinoceptor-blocking drugs. Adrenergic transmission: adrenoceptor-activating and other sympathomimetic drugs; adrenoceptor antagonist drugs. Drugs with actions on smooth muscle: Eicosanoids, Nitric oxide and Purines. Endocrine drugs: pharmacology of Hypothalamic and Pituitary hormones; pharmacology of Thyroid and antithyroid drugs; Adrenocorticosteroids and adrenocortical antagonists; Gonadal hormones and antagonists; Agents that affect bone mineral homeostasis; pharmacology of diabetes.
LAB CLASSES PROGRAM (Laboratory of Pharmacology, ICBAS – UP)
Introduction to laboratory procedures. - Lab animal welfare and handling. - salicylic acid uptake in an acidic and basic gastric environment in rat. - Biotransformation of zoxozolamine “in vitro”. - Observation of the action of hepatic microsomes. - The effects of local anaesthetics in hypotonic haemolysis of rat erythrocytes. - Comparison of the anaesthetic effect of procaine and cocaine in the cornea of guinea pig. The influence of vasoconstrictors in the duration of local anaesthesia. - Action of anti-epileptics in nervous conduction. - Relaxing muscle agents (depolarizing and non-depolarizing)
EXTRAMURAL HANDS-ON CLASSES (Campus Agrário de Vairão, ICAV – UP)
Safety in drugs storage and handling. Introduction to the administration of drugs in different species. Material necessary for performing different administration routes. The routes include:
-Large ruminants: oral (solid and liquid), gastric intubation, subcutaneous, intradermal, intramuscular and intravenous.
-Small ruminants: oral (solid and liquid), gastric intubation, subcutaneous, intradermal, intramuscular and intravenous.
-Equines: oral (liquid), subcutaneous, intradermal, intramuscular and intravenous.
-Dogs: oral (solid and liquid), subcutaneous, intradermal, intramuscular and intravenous.
THEORETICAL-PRACTICAL CLASSES (Laboratory of Pharmacology, ICBAS – UP) - The subject varies each year
-Pharmacological treatment of idiopathic epilepsy in dogs
-The COXIB NSAIDs: clinical and pharmacologic importance in veterinary medicine
-Anaesthesia and analgesia for geriatric veterinary patients
-Therapeutic approach to feline diabetes – the role of incretins
-Prostaglandins and reproduction
-Pharmacotherapy for Behavioral Disorders in Pet Birds
-The teaching methodology includes theoretical, theoretical-practical and practical classes, as the following:
Theoretical classes: Video projection (Data-Show).
Theoretical-Practical lessons: Presentation and discussion of themes related to the laboratory work and to clinical practice.
Practical lessons: Focus on experimental work at the Laboratory of Pharmacology (ICBAS), and drugs administration at the ICAV/UP (Vairão).
Attendance to theoretical/practical and practical classes is mandatory.
Designation | Weight (%) |
---|---|
Exame | 37,50 |
Prova oral | 32,50 |
Trabalho de campo | 7,50 |
Trabalho escrito | 15,00 |
Trabalho laboratorial | 7,50 |
Total: | 100,00 |
Practical Evaluation (compulsory, 6 points)
1. Monography (3 points): Oral presentation of a new/relevant matter of importance to laboratory work and to clinical practice. Presentation of a written piece of work (monograph). Team work (3-4 students). Oral presentation (» 20 min) and oral discussion (» 10 min)
2. Presentation / report of practical work (sorted group) (1.5 points): Practical report realizado no fim da aula prática. Instructor’s continuous Assessment
3. Performance of drug administrations / Instructor’s information (1,5 scores): Instructor’s continuous Assessment (0.5 valor). Each student will be classified by her/his performance in the practical work.
Practical classification is valid for two years after achievement.
Theoretical Evaluation (14 points): Final examination (test + oral evaluation).
Test: Multiple choice questions / Correspondences / Short answer.
Admission conditions: *75% attendance to practical lessons, *3.0/6.0 points in the practical course.
Oral examination: Waived if final classification in the test is higher than * 7.5/14.0 points. Compulsory if final classification in the test is higher than * 6.0/14.0 points. Failure if final classification in the test is lowed than * 6.0/14.0 points.
Final Score= 0.3* practical classes score + 0.7* Theoretical Exam Score
Practical classes score = 0,15*Monograph + 0,075* Practical classes + 0,075*Drug administration routes classes
1. Monography (3 points): Oral presentation of a new/relevant matter of importance to laboratory work and to clinical practice. Presentation of a written piece of work (monograph). Team work (3-4 students). Oral presentation (» 20 min) and oral discussion (» 10 min)
2. Presentation / report of practical work (sorted group) (1.5 points): Practical report realizado no fim da aula prática. Instructor’s continuous Assessment
3. Performance of drug administrations / Instructor’s information (1,5 scores): Instructor’s continuous Assessment. Each student will be classified by her/his performance during the practical work.
Oral examination
Oral examination