Basic Immunology

Code:

MT241

Acronym:

I_BASI

Keywords
Classification	Keyword
OFICIAL	Medicine

Instance: 2004/2005 - 2S

Active?	Yes
Responsible unit:	Imuno-Physiology and Pharmacology
Course/CS Responsible:	Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MED	122	Plano oficial a partir de 2003	2	3		-

Objectives

1. Aquisition of knowledge in basic Immunology.
2. Development of rational mechanisms that will allow the resolution of questions arising on other academic courses or in the professional activity.
3. Aquisition of self-learning methods and practices.
4. Aquisition of knowledge on immunological techniques potentially useful in diagnosis and improvement on laboratory skills.

Program

1. Introduction to the immune system.
1.1. Basic aspects of the immune system
1.2. Central and peripheral lymphiod organs.
2. Molecular and cellular structural components of the immune system and antigen recognition.
2.1. Hematopoietic development and characteristics of non-lymphiod cells of the immune system
2.2. Immunoglobulins.
2.3. Antigen-antibody reactions.
2.4. T-cell receptor (TCR).
2.4. Immunoglobulin and TCR gene rearrangement.
2.5. MHC.
3. Ontogeny and dynamics of lymphocyte populations. Functional aspects of the structural components of the immune system.
3.1. B-cell ontogenic differentiation and activation
3.2. T-cell activation and B-/T-cell cooperation.
3.3. T- and NK-cell maturation.
4. Effector immune mechanisms.
4.1. Citokines. Dendritic cells and T-cell differentiation.
4.2. Complement.
4.3. Linfocyte recirculation. Adhesion molecules. Inflammation.
4.4. Immune response in infectious conditions.
4.5. Vaccines.
5. The immune system in physiological and pathological conditions.
5.1. Tolerance and autoimmunity.
5.2. Hipersensibility reactions.
5.3. Blood groups and and feto-maternal incompatibility.
5.4. Transplantation.
5.5. Immunodeficiencies.
5.6. AIDS

Main Bibliography

Kuby, J. Immunology. 2003. Freeman Ed.

Complementary Bibliography

Review articles in the field of basic and clinical immunology.

Teaching methods and learning activities

Theoretical classes
Laboratory classes

Software

Class presentations available in PDF format at this website

Evaluation Type

Distributed evaluation with final exam

Eligibility for exams

Attaining of a minimum of 2/3 of the laboratory classes is necessary.

Calculation formula of final grade

Mean classification of the 2 partial tests or, alternatively, final exam

Examinations or Special Assignments

According to the general law

Classification improvement

Continuous assessment