In vitro experimental assessment of cardiac function

• Type: Chapter or Part of a Book
• Date: 2015

Authors

Falcao Pires, I (Author) FMUP; Leite-Moreira AF (Author) FMUP

Book

Title: Introduction to Translational Cardiovascular Research

Pages: 371-388

ISBN: 9783319087986; 9783319087979

Electronic ISBN: 978-3-319-08798-6

Indexing

Scopus - 2 Citations

Other information

Authenticus ID: P-00S-GFM

DOI: 10.1007/978-3-319-08798-6_20

Abstract (EN): The increasing number of animal models available has undoubtedly contributed to the great advances in cardiovascular research. Not with standing the development of these valuable tools, it is important to properly assess myocardial function both in physiological and in pathological conditions as well as in response to certain drugs. It is clear from recent literature that significant technological progresses to evaluate cardiac function has been made over the last 10 years. This progress has substantially overcome many of the difficulties associated with cardiovascular function assessment in disease models. Moreover by means of a reductionist approach it has been possible to dissect the complexities of in vivo heart function using more detailed and sensitive in vitro techniques that are able to exclude confounding factors of the in vivo setting. Thus many new questions are constantly arising and additional experiments and methodologies urge. © Springer International Publishing Switzerland 2015.

Language: English

Type (Professor's evaluation): Scientific