Oncobiology

Code:

MO01

Acronym:

ONC

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2024/2025 - 1S (of 16-09-2024 to 14-02-2025)

Active?	Yes
Responsible unit:	Molecular Pahology and Immunology
Course/CS Responsible:	Master Degree in Oncology

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MO	22	Oficial plan since 2023	1	-	3	21	81

Teaching language

Portuguese

Objectives

To know the basic concepts of the molecular classification of the various neoplasias;

To undestand the main mechanisms of carcinogenesis and tumor progression;

To identity the mais hereditary predisposition syndromes;

To understand the concepts and to identify examples of molecular targeted therapy.

Learning outcomes and competences

Knowledge on the basic concepts of the molecular classification of the various neoplasias;

Undestanding of the main mechanisms of carcinogenesis and tumor progression;

Identification of the main hereditary predisposition syndromes;

Understanding the concepts and to identify examples of molecular targeted therapy.

Working method

Presencial

Pre-requirements (prior knowledge) and co-requirements (common knowledge)

The same as for acess to the Master degree.

Program

Why is it important to understand the biology of cancer? A paradigmatic example

Chromosomal rearrangements and differential diagnosis in hematologic diseases and sarcomas

Molecular subclassification of breast cancer and its prognostic and therapeutic value

Mutations in genes involved in cell signaling and therapeutic implications in colorectal cancer and melanoma

Molecular classification and targeted therapy in lung cancer

Cell cycle regulation genes and hereditary predisposition

Clinical impact of DNA repair deficiency by homologous recombination

Biological mechanisms and clinical impact of DNA mismatch repair deficiency

Pathobiological and phenotypic heterogeneity of polyposes

Biological mechanisms and clinical impact of cell adhesion inhibition

Pathogenesis of endocrine neoplasias and its clinical relevance

Research on the pathogenetic mechanisms of prostate cancer

Mandatory literature

Kumar Vinay 070; Robbins and Cotran pathology basis of disease. ISBN: 0-7216-9274-5

Teaching methods and learning activities

Theorectical-practical classes

Software

Moodle

keywords

Health sciences > Medical sciences > Medicine > Oncology
Health sciences > Medical sciences > Medicine > General pathology

Evaluation Type

Evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	100,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Estudo autónomo	58,00
Frequência das aulas	23,00
Total:	81,00

Eligibility for exams

Attendance of at least 2/3 of the classes.

Calculation formula of final grade

Evaluation by final written exam com multiple choice questions.

Examinations or Special Assignments

There are no special exams or assignments.

Special assessment (TE, DA, ...)

Those indicated by the evaluation and pedagogic norms of Porto University. The dates will be defined by the Pedagogical council.

Classification improvement

Improvement of the classification can be performed according to the schedule approved by the Pedagogical Council.

Observations

The recommended bibliography and copy of lecture slides with be placed in the Moodle platform.
http://moodle.up.pt/