Immunology
Keywords |
Classification |
Keyword |
OFICIAL |
Basic Sciences |
Instance: 2012/2013 - 2S
Cycles of Study/Courses
Acronym |
No. of Students |
Study Plan |
Curricular Years |
Credits UCN |
Credits ECTS |
Contact hours |
Total Time |
MIMV |
115 |
Plan 2007 to 2017 |
2 |
- |
5 |
64 |
135 |
Teaching language
Portuguese
Objectives
1. Acquisition of knowledge and skills on fundamental immunology, emphasizing the particular specificities of different domestic animals.
2. Acquisition of skills helpful for a better understanding of basic and advanced bibliographic information in the area of immunology.
3. Acquisition and development of rational mechanisms useful for the interpretation of immunological data and resolution of immunological problems.
4. Acquisition of skills for self-oriented study, including the correct usage of specific databases.
5. Improvement of communication skills regarding oral and written transmission of knowledge.
6. Acquisition of skills and knowledge on specific immunological diagnostic techniques.
7. Improvement of laboratory skills.
Program
1. Introduction to the immune system.
1.1. General introduction to the immune system.
2. Innate Immunity
2.1. Effector mechanisms (phagocytic cells, complement, inflammation).
2.2. Pathogen-associated molecular patterns (PAMPs) and their recognition (PRRs).
3. Cellular and mollecular components of the immune system and antigen recognition.
3.1. Central and perypheral lymphiod organs. Diffuse lymphoid tissue.
3.2. Hematopoietic development.
3.3. Immunoglobulins. B-cell receptor (BCR).
3.4. Antigen-antibody reactions.
3.5. V(D)J recombination and generation of diversity in immunoglobulins and T-cell eceptor (TCR).
3.6. TCR, Structure and function.
3.7. MHC. Antigen presentation.
4. Ontogeny and dinamics of lymphoid populations.
4.1. Ontogeny and activation of B-cells.
4.2. Maturation of T and NK cells.
4.3. Activation of T-cells and B-T-cell cooperation.
5. Effector Mechanisms.
5.1. Citokynes. Differentiation and function of T-cells.
5.2. Immune response during infection.
5.3. Immunity in body surfaces
5.4. Vaccines.
6. The immune system in physiological and pathologycal conditions.
6.1. Hypersensitivity reactions.
6.2. Tolerance and autoimmunity.
6.3. Transplantation.
6.4. Primary and secondary immunodeficiencies.
7. Immunologycal methods
7.1. Separation of human blood mononuclear cells
7.2. Morphology of lymphoid organs.
7.3. Production of monoclonal antibodies.
7.4. B-cell response to a mitogen. Measurement of serum immunoglobulins by using “Sandwich-ELISA”.
7.5. Assessment of the primary immune response to an antigen. Hemolytic Plaques.
7.6. Flow cytometry
7.7. Immunopathology
Mandatory literature
Tizard, Ian; Veterinary Immunology. An Introduction , Saunders, 2008. ISBN: 978-1416049890
Teaching methods and learning activities
Theoretical classes , Laboratory classes, presentation of scientific papers by the students.
keywords
Health sciences > Medical sciences > Veterinary medicine > Animal immunology
Evaluation Type
Distributed evaluation with final exam
Assessment Components
Description |
Type |
Time (hours) |
Weight (%) |
End date |
Attendance (estimated) |
Participação presencial |
56,00 |
|
|
|
Exame |
2,00 |
|
|
|
Exame |
2,00 |
|
|
|
Exame |
2,00 |
|
|
|
Exame |
2,00 |
|
|
|
Defesa pública de dissertação, de relatório de projeto ou estágio, ou de tese |
0,50 |
|
|
|
Total: |
- |
0,00 |
|
Eligibility for exams
Participation in a minimum of 3/4 of the laboratory classes
Calculation formula of final grade
Sum of:
Mark on theoretical tests or exam (up to 15)
mark obtained on scientific papers presentations (up to 3,0)
Active participation on classes along the year (oral or written) (up to 2,0).
Minimum of 6,5 on each partial test necessary for approval
Examinations or Special Assignments
Oral paper presentations.
Answers to written small questionnaires
Special assessment (TE, DA, ...)
According to general law, and specific rules approved by ICBAS
Classification improvement
According to general law, and specific rules approved by ICBAS
Observations
Lecturing will not be based or folow a given textbook. The recomended bibliography should thus be considered as complementary material to that presented in the course classess