Diet-Induced Microbiome's Impact on Heart Failure: A Double-Edged Sword

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2023

Autores

Rodrigues, A (Autor) Outra; Goncalves, A (Autor) Outra; Morais, J (Autor) Outra; Araujo, R (Autor) Outra; Falcao Pires, I (Autor) FMUP

Revista

Título: Nutrients

Vol. 15 Nº 4

Página Final: 1223

ISSN: 2072-6643

Editora: MDPI

Indexação

ISI Web of Knowledge - 3 Citações

Scopus

Outras Informações

ID Authenticus: P-00X-ZDA

DOI: 10.3390/nu15051223

Abstract (EN): Heart failure (HF) is a debilitating disease with a significant clinical and economic impact worldwide. Multiple factors seem to increase the risk of developing HF, such as hypertension, obesity and diabetes. Since chronic inflammation plays a significant role in HF pathophysiology and gut dysbiosis is associated with low-grade chronic inflammation, the risk of cardiovascular diseases is likely modulated by the gut microbiome (GM). Considerable progress has been made in HF management. However, there is a need to find new strategies to reduce mortality and increase the quality of life, mainly of HFpEF patients, since its prevalence continues to rise. Recent studies validate that lifestyle changes, such as diet modulation, represent a potential therapeutic approach to improve several cardiometabolic diseases, although their effects on the GM and its indirect cardiac impact still warrant further research. Hence, in this paper, we aim to clarify the link between HF and the human microbiome.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 16