Abstract (EN):
Primary liver tumors in children and adolescents include a wide and complex spectrum of epithelial, mesenchymal and vascular neoplasms, ranging from benign, incidentally discovered lesions to malignant entities. A high level of suspicion is usually required for an early diagnosis of these tumors, due to their rarity and unspecific clinical presentation. The current knowledge on the clinical, analytical and imaging features as well as on the (molecular) pathology profile contributes for an earlier diagnosis, with prognostic and therapeutic implications. This paper reviews the epidemiology, etiopathogenesis, histopathology and molecular features of the most common primary liver tumors in pediatric population.
Idioma:
Inglês
Tipo (Avaliação Docente):
Científica