Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages

• Tipo: Artigo em Revista Científica Internacional
• Data: 2006

Autores

Soares, PA (Autor) Outra; Pereira, F (Autor) Outra; Brion, M (Autor) Outra; Alves, C (Autor) Outra; Richards, M (Autor) Outra; Carracedo, A (Autor) Outra; Amorim, A (Autor) FCUP; Gusmao, L (Autor) Outra

Revista

Título: International Congress Series

Vol. 1288

Páginas: 82-84

ISSN: 0531-5131

Editora: Elsevier B.V.

Indexação

ISI Web of Knowledge

Scopus - 3 Citações

Outras Informações

ID Authenticus: P-007-FDH

DOI: 10.1016/j.ics.2005.09.173

Abstract (EN): Y specific microsatellites (STRs) have been widely used in forensic and population genetics in age estimates of human male lineages. Previously, estimates of mutation rates from father-son pairs have given quite variable results in different studies, essentially due to the rarity of mutations. We propose an indirect approach for determining relative mutation rates of Y-chromosome microsatellites based on STR allele size intra-lineage variance. Indeed, the present distribution of STR alleles offers us an insight into the mechanisms that have generated that diversity.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3