Process intensification and optimization for hydroxyapatite nanoparticles production

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

Filipa Castro (Autor) FEUP; Simon Kuhn (Autor) Outra; Klavs Jensen (Autor) Outra; António Ferreira (Autor) FEUP; Fernando Rocha (Autor) FEUP; António Vicente (Autor) Outra; José António Teixeira (Autor) Outra

Revista

Título: Chemical Engineering Science

Vol. 100

Páginas: 352-359

ISSN: 0009-2509

Editora: Elsevier

Indexação

ISI Web of Knowledge - 42 Citações

ISI Web of Science

Scopus - 46 Citações

INSPEC

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia química

CORDIS: Ciências Tecnológicas > Engenharia > Engenharia química

Projetos Associados

UI0511 - PROJECTO ESTRATÉGICO - UI 511 - 2013-2014

Outras Informações

ID Authenticus: P-006-83N

DOI: 10.1016/j.ces.2013.01.002

Abstract (EN): Precipitation processes are widely used in industry for the production of particulate solids. Efficient mixing of the reagents is of major importance for the chemical and physical nature of the synthesized particles. Recently, microreactors have been studied to overcome homogeneity problems found when using stirred tank batch reactors. The present work investigated an ultrasonic tubular microreactor for the continuous-flow precipitation of hydroxyapatite (HAp), both in single-phase flow (SPF) and in gas-liquid flow (GLF). HAp nanoparticles were yielded for both configurations under near-physiological conditions of pH and temperature. The as-prepared particles, especially those that were prepared under GLF, show improved characteristics compared to commercial powder or powder obtained in a stirred tank batch reactor. Primary particles are smaller, particle shape is more homogeneous, and the aggregation degree of the particles is lower.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8