Production of porous hydroxyapatite with potential for controlled drug delivery

• Tipo: Artigo em Revista Científica Internacional
• Data: 2004

Autores

A. C. Queiróz (Autor) Outra; S. Teixeira (Autor) Outra; José D. Santos (Autor) FEUP; Fernando J. Monteiro (Autor) FEUP

Revista

Título: Materials Science Forum

Vol. 455-456

Páginas: 358-360

ISSN: 0255-5476

Editora: Trans Tech Publications Ltd

Indexação

ISI Web of Science

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia dos materiais

CORDIS: Ciências Tecnológicas > Engenharia > Engenharia de biomateriais

Outras Informações

DOI: 10.4028/www.scientific.net/MSF.455-456.358

Abstract (EN): Porous hydroxyapatite was prepared in order to be used as a drug carrier and promote bone ingrowth. For this purpose, the microstructure should have interconnective pores and micro as well as macro porosity, for bone cell adhesion and bone ingrowth. The porous hydroxyapatite prepared by the burn-out method exhibits all these features. For measuring porosity, SEM analysis, mercury intrusion porosimetry and BET were used. FT-IR and XRD analysis revealed that only hydroxyapatite phase was present, being this result similar to the one found for dense samples. The morphology obtained appears to be well adapted to bone growth and drug adsorption.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3