Epicardial adipose tissue volume is not an independent predictor of atrial fibrillation recurrence after catheter ablation; [El tejido adiposo epicárdico no es un predictor independiente de recurrencia de fibrilación auricular tras ablación con catéter]

• Tipo: Artigo em Revista Científica Internacional
• Data: 2023

Autores

Cruz, I (Autor) Outra; Lopes Fernandes, S (Autor) Outra; Diaz, O (Autor) Outra; Saraiva, F (Autor) Outra; Barros, S (Autor) FMUP; Primo, J (Autor) Outra; Sampaio, F (Autor) Outra; Ladeiras Lopes, R (Autor) Outra; Fontes-Carvalho R (Autor) FMUP

Revista

Título: Revista Espanola de Cardiologia

Vol. 76

Páginas: 539-547

ISSN: 0300-8932

Editora: Elsevier

Indexação

Scopus - 5 Citações

Outras Informações

ID Authenticus: P-00Y-845

DOI: 10.1016/j.recesp.2022.11.006

Abstract (EN): Introduction and objectives: Previous studies have suggested that epicardial adipose tissue (EAT) could exert a paracrine effect in the myocardium. However, few studies have assessed its role in the risk of atrial fibrillation (AF) recurrence. This study aimed to evaluate the association between EAT volume, and its attenuation, with the risk of AF recurrence after AF ablation. Methods: A total of 350 consecutive patients who underwent AF ablation were included. The median age was 57 [IQR 48-65] years and 21% had persistent AF. Epicardial fat was quantified by multidetector computed tomography using Syngo.via Frontier-Cardiac Risk Assessment software, measuring pericardial fat volume (PATV), EAT volume, and attenuation of EAT posterior to the left atrium. AF recurrence was defined as any documented episode of AF, atrial flutter, or atrial tachycardia more than 3 months after the procedure. Results: After a median follow-up of 34 [range, 12-57] months, 114 patients (33%) had AF recurrence. Univariable Cox regression showed that patients with an EAT volume ¿ 80 mL had an increased risk of AF recurrence (HR, 1.65; 95%CI, 1.14-2.39; P = .007). However, after multivariable adjustment, EAT volume did not remain an independent predictor of AF recurrence (HR, 1.24; 95%CI, 0.83-1.87; P = .3). Similar results were observed with PATV. Patients with lower attenuation of EAT did not have a higher risk of AF recurrence (log-rank test, P = .75). Conclusions: EAT parameters including the evaluation of EAT volume, PATV and EAT attenuation were not independent predictors of AF recurrence after catheter ablation. © 2022 Sociedad Española de Cardiología

Idioma: Inglês

Tipo (Avaliação Docente): Científica