Inflammatory granulocytes decrease subcutaneous growth of melanoma in mice

• Tipo: Artigo em Revista Científica Internacional
• Data: 2004

Autores

Costa, MM (Autor) ICBAS; AP Águas (Autor) ICBAS

Revista

Título: Inflammation

Vol. 28

Páginas: 355-357

ISSN: 0360-3997

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 1 Citação

Outras Informações

ID Authenticus: P-000-7GB

DOI: 10.1007/s10753-004-6646-7

Abstract (EN): Growing melanomas invade the subcutaneous tissues. We have compared the size of tumors implanted in the subcutaneous cavities of C57BL/6 mice where inflammatory reactions were induced before the injection of 5x10(5) melanoma cells (B16F10 cell line). Granulocytic inflammation of the subcutaneous cavities resulted in a significant decrease in the growth of the implanted melanomas, whereas monocytic inflammation had no effect on tumor growth. We conclude that granulocytes, but not monocytes/macrophages, have anti-tumor action on melanoma that invade the subcutaneous tissues.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3