Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2010

Autores

Mendes, RA (Autor) Outra; Carvalho, JFC (Autor) Outra; van der Waal, I (Autor) Outra

Revista

A Revista está pendente de validação pelos Serviços Administrativos.

Título: ORAL ONCOLOGY

Vol. 46

Páginas: 219-225

ISSN: 1368-8375

Indexação

ISI Web of Knowledge - 73 Citações

Scopus - 96 Citações

Outras Informações

ID Authenticus: P-003-82P

DOI: 10.1016/j.oraloncology.2010.01.012

Abstract (EN): Keratocystic odontogenic tumor (KCOT), formerly referred to as odontogenic keratocyst, is a benign neoplasm of odontogenic origin which may present an aggressive and infiltrative behavior leading to high recurrence rates. A review of the various treatment modalities, ranging from simple enucleation to radical surgery is portrayed in relation to clinical, radiological, histopathological and molecular features. Although prognostic factors based on clinico-pathologic and immunohistochemical findings for determining the potential for recurrence of KCOT still remains unclear, its use for determining the potential for recurrence of KCOT after surgical treatment may become important to successfully manage this neoplasm's aggressive behavior. The key element for future management of KCOTs will probably be based on thorough knowledge of the biological basis of this tumor, thereby enabling a more tailored treatment approach.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7