Exudative versus Nonexudative Age-Related Macular Degeneration: Physiopathology and Treatment Options

• Tipo: Artigo em Revista Científica Internacional
• Data: 2022

Autores

Fernandes, AR (Autor) Outra; Zielinska, A (Autor) Outra; Sanchez Lopez, E (Autor) Outra; dos Santos, T (Autor) Outra; Garcia, ML (Autor) Outra; Silva, AM (Autor) Outra; Karczewski, J (Autor) Outra; Souto, EB (Autor) FFUP

Revista

Título: International Journal Of Molecular Sciences

Vol. 23

Página Final: 2592

ISSN: 1661-6596

Editora: MDPI

Indexação

ISI Web of Knowledge - 1 Citação

Scopus - 2 Citações

Outras Informações

ID Authenticus: P-00W-7XX

DOI: 10.3390/ijms23052592

Abstract (EN): Age-related macular degeneration (AMD) is an eye disease typically associated with the aging and can be classified into two types-namely, the exudative and the nonexudative AMD. Currently available treatments for exudative AMD use intravitreal injections, which are associated with high risk of infection that can lead to endophthalmitis, while no successful treatments yet exist for the nonexudative form of AMD. In addition to the pharmacologic therapies administered by intravitreal injection already approved by the Food and Drug Administration (FDA) in exudative AMD, there are some laser treatments approved that can be used in combination with the pharmacological therapies. In this review, we discuss the latest developments of treatment options for AMD. Relevant literature available from 1993 was used, which included original articles and reviews available in PubMed database and also information collected from Clinical Trials Gov website using age-related macular degeneration and antiangiogenic therapies as keywords. The clinical trials search was limited to ongoing trials from 2015 to date.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 23