Beyond central adiposity: Liver fat and visceral fat area are associated with metabolic syndrome in morbidly obese patients

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Faria, Gil (Autor) ICBAS; Goncalves, A (Autor) Outra; Cunha, R (Autor) Outra; guimaraes, jt (Autor) FMUP; Conceicao Calhau (Autor) FMUP; John Preto (Autor) Outra; Gomes AT (Autor) FMUP

Revista

Título: International Journal of Surgery

Vol. 14

Páginas: 75-79

ISSN: 1743-9191

Editora: Elsevier

Indexação

ISI Web of Knowledge - 18 Citações

Scopus - 18 Citações

Outras Informações

ID Authenticus: P-00A-89C

DOI: 10.1016/j.ijsu.2014.12.028

Abstract (EN): Background: Despite its widespread clinical use, both body mass index (BMI) and waist circumference have been reported as inaccurate methods to measure abdominal obesity. The main objective of this study was to determine the relation between visceral fat area and fatty liver infiltration with the expression of metabolic syndrome (MS) in morbidly obese patients. Methods: We recruited a random selection of 100 morbidly obese patients on pre-operative evaluation for bariatric surgery. A pre-operative CT slice at L4-L5 level, was performed to measure visceral fat and at T12 level to measure hepatic attenuation. Results: Patients with MS had lower hepatic attenuation values (median 49.9 vs 55.5HU; p = .018) and had more VAT (242 vs 172 cm(2); p = .001). Conventional measures (BMI: p = .729 and waist circumference: p = .356), were not useful in discriminating morbidly obese patients with MS. By multivariable logistic regression, fatty liver infiltration (OR = 5.3; p = .03) and age (OR = 1.08; p = .04) were the only factors independently related to the presence of MS. MS prevalence was 100%, 71% and 55%, respectively for patients with both fatty liver and visceral adiposity; one; or none of this findings (AUC -.715; p = .016). Conclusion: CT scan seems to measure 2 important markers of MS: visceral adiposity and hepatic fatty infiltration. In morbidly obese patients, both visceral adiposity and hepatic fatty infiltration increase the risk for the presence of MS.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5